White Paper – Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy

White Paper - Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy

White Paper - Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy

 

Enhance Your Gene Therapy Strategy with Key AAV Insights

Gene therapy is advancing rapidly, with adeno-associated virus (AAV) vectors at the forefront, offering hope for patients with genetic disorders. However, the success of these therapies hinges on a crucial aspect that can no longer be overlooked—immunogenicity. "Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy" exams the complex interplay between AAV vectors and the immune system.

 

Our white paper provides an exploration into the challenges and innovative solutions to AAV immunogenicity. With immunogenicity being a potential barrier to therapeutic success, it's imperative for pharmaceutical developers to be equipped with the knowledge and strategies to mitigate these obstacles. This document serves as a cornerstone, paving the way for safer and more efficacious gene therapies by emphasizing the importance of AAV antibody testing as part of the regulatory approval process.

 

Quest Diagnostics is not just a collaborator but a pioneer in AAV antibody testing, ensuring that gene therapies not only reach their therapeutic potential but also gain swift regulatory approval. Our white paper equips you with the knowledge to navigate this complex landscape confidently.

 

Are you ready to pioneer precision in gene therapy? We invite pharmaceutical partners and industry innovators to download "Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy" and join us in shaping the future of gene therapy.

 

Highlights/summary:

  • Gene therapy is advancing rapidly, with adeno-associated virus (AAV) vectors at the forefront, offering hope for patients with genetic disorders.
  • This white paper is free and can be downloaded and read at your convenience.


About the authors:




Whitepaper - Advanced AAV Antibody Testing: Pioneering Precision in Gene Therapy

  • Brian Sansoucy BS, MBA

    Scientific Director, Immunology R&D, Quest Diagnostics Brian has a BS in biology and biotechnology from Worcester Polytechnic Institute and an MBA from the Isenberg School of Management at University of Massachusetts Amherst. He has more than 15 years in the diagnostics industry serving in roles in laboratory operations and R&D. In his current role as a scientific director for R&D Immunology, he oversees a group of scientists that develop immunoassays support Quest Diagnostics testing and custom assay testing for pharmaceutical clients.

  • Christian Tagwerker PhD

    Scientific Director, Immunology R&D, Quest Diagnostics Christian Tagwerker PhD provides 20+ years of experience in research and clinical laboratory methods development, with a focus on synthetic biology, next-generation sequencing (NGS), proteomics, lab setup and automation. An expert in protein-protein interactions and modifications, Dr. Tagwerker’s publications involved protein identification methods and associated cloning technologies yielding new insights related to human cancer and disease. An ASCP-C Technologist, licensed CLIA Laboratory Director and Board-certified Clinical Chemist and Toxicological Chemist (NRCC), Dr. Tagwerker received his PhD in Biochemistry and Molecular Biology from Leopold-Franzens Universität (LFU) Innsbruck, Austria in collaboration with the Department of Biochemistry, UC Irvine.

  • Greg Baschkopf

    Executive Director, IVD and CDx, Quest Diagnostics Greg Baschkopf, currently the Executive Director of IVD and CDx at Quest Diagnostics, is a dynamic leader in the field of healthcare diagnostics. With a decade at Quest, his journey from medical technologist to his current executive role highlights his deep commitment to innovation in diagnostics. His expertise in molecular oncology, genetics, and solid tumor profiling, combined with his progression through various leadership roles, showcases his ability to drive impactful changes in clinical trials and diagnostic developments. Baschkopf's educational background in biology from Boston University complements his professional achievements, underscoring his comprehensive understanding of the scientific and operational aspects of healthcare diagnostics. His career at Quest Diagnostics, marked by significant contributions to the field, reflects his dedication to advancing healthcare outcomes through innovative diagnostic solutions.

  • Vijay Walia

    Sr. Director, CDx Programs, Quest Diagnostics Vijay Walia's role as Senior Director of CDx Programs at Quest Diagnostics is a testament to his specialized focus in companion diagnostics and regulatory affairs, particularly within the niche of health technology. His journey, starting with foundational roles at the FDA, shaped his expertise in overseeing critical health technology projects. This background, coupled with his scientific training in pharmacology, has been integral to his success at Quest, where he drives innovations in diagnostic methodologies. His career illustrates a deep commitment to advancing specific areas of healthcare through a combination of regulatory knowledge and technical proficiency.

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