NEWTON, Mass., Oct. 18, 2018 (GLOBE NEWSWIRE) — Allena Pharmaceuticals, Inc. (NASDAQ:ALNA), a late-stage, biopharmaceutical company dedicated to developing and commercializing first-in-class, oral enzyme therapeutics to treat patients with rare and severe metabolic and kidney disorders, today announced presentations at two upcoming medical meetings. At the 2018 American College of Rheumatology (ACR/ARHP) Annual Meeting held October 19-24th in Chicago, IL, the company will present proof-of-concept data for ALLN-346, its lead product candidate for the treatment of hyperuricemia in the setting of advanced chronic kidney disease (CKD). In addition, at the American Society of Nephrology (ASN) Kidney Week 2018 held October 23-28th in San Diego, CA, the company will present results from a retrospective analysis characterizing the unmet need in enteric hyperoxaluria and an overview of the design of the ongoing Phase 3 URIROX-1 clinical trial evaluating the safety and efficacy of reloxaliase, its lead product candidate for the treatment of enteric hyperoxaluria.
Details on the presentations are as follows:
2018 ACR/ARHP Annual Meeting
| Title: | A Novel Recombinant Oral Urate Oxidase (UrOx) ALLN-346 Reduces Severe Hyperuricemia and Normalizes Hyperuricosuria in Nephropathic UrOx Knockout (UrOxKO) Mice | |
| Session Title: | Metabolic and Crystal Arthropathies – Basic and Clinical Science Poster I | |
| Session Date and Time: | Monday, October 22, 2018; 9:00 a.m. – 11:00 a.m. CT (10:00 a.m. – 12:00 p.m. ET) | |
| Location: | Poster Hall, McCormick Place West | |
| Abstract ID: | 1299 |
The accepted abstract is now available online on the ACR/ARHP website at www.acrabstracts.org.
ASN Kidney Week 2018
| Title: | Unmet Need in Enteric Hyperoxaluria: Clinical Characteristics and Stone Burden in Patients from ALLN-177 Studies | |
| Session Title: | Bone and Mineral Metabolism: Clinical – II | |
| Session Date and Time: | Saturday, October 27, 2018; 10:00 a.m. – 12:00 p.m. PT (1:00 p.m.-3:00 p.m. ET) | |
| Location: Abstract ID: |
Exhibit Hall, San Diego Convention Center SA-PO685 |
| Title: | Evaluate the Safety and Efficacy of ALLN-177 in Patients with Enteric Hyperoxaluria (UriRox-1) | |
| Session Title: | Informational Posters | |
| Session Date and Time: | Thursday, October 25, 2018; 10:00 a.m. – 12:00 p.m. PT (1:00 p.m.-3:00 p.m. ET) | |
| Location: Abstract ID: |
Exhibit Hall, San Diego Convention Center INFO34 |
The accepted abstracts are now available online on the ASN Kidney Week website at: https://www.asn-online.org/education/kidneyweek/2018/program-search-abstract.aspx.
About Allena Pharmaceuticals
Allena Pharmaceuticals, Inc. is a late-stage biopharmaceutical company dedicated to developing and commercializing first-in-class, oral enzyme therapeutics to treat patients with rare and severe metabolic and kidney disorders. Allena’s lead product candidate, reloxaliase, is a first in class, oral enzyme therapeutic for the treatment of hyperoxaluria, a metabolic disorder characterized by markedly elevated urinary oxalate levels and commonly associated with kidney stones, chronic kidney disease and other serious kidney disorders.
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