{"id":554832,"date":"2017-11-07T21:05:00","date_gmt":"2017-11-07T21:05:00","guid":{"rendered":"https:\/\/www.pm360online.com\/?guid=e324564ad432f1a93031e46bad7a485e"},"modified":"2017-11-07T21:05:00","modified_gmt":"2017-11-07T21:05:00","slug":"tesaro-announces-third-quarter-2017-operating-results","status":"publish","type":"post","link":"https:\/\/www.pm360online.com\/tesaro-announces-third-quarter-2017-operating-results\/","title":{"rendered":"TESARO Announces Third-Quarter 2017 Operating Results"},"content":{"rendered":"<ul>\n<li><strong>ZEJULA<sup>\u00ae<\/sup> was the most prescribed PARP inhibitor in U.S. with Q3 net sales of $39.4 million<\/strong><\/li>\n<li><strong>Positive CHMP opinion issued for ZEJULA in E.U.; commercial launch anticipated to begin by year-end<\/strong><\/li>\n<li><strong>Expansion of niraparib development program underway for multiple tumor types<\/strong><\/li>\n<li><strong>VARUBI<sup>\u00ae<\/sup> IV approved by U.S. FDA; commercial launch planned for November<\/strong><\/li>\n<li><strong>Phase 1 combination study of TSR-022 (anti-TIM-3) and TSR-042 (anti-PD-1) now enrolling patients<\/strong><\/li>\n<li><strong>Phase 1 study of TSR-033 (anti-LAG-3) now enrolling patients<\/strong><\/li>\n<\/ul>\n<p align=\"justify\">WALTHAM, Mass., Nov.  07, 2017  (GLOBE NEWSWIRE) &#8212; TESARO, Inc. (NASDAQ:<a href=\"http:\/\/globenewswire.com\/News\/Listing?symbol=TSRO&#038;exchange=2\">TSRO<\/a>), an oncology-focused biopharmaceutical company, today reported operating results for third-quarter 2017 and provided an update on the Company&#8217;s commercial products and development programs.<\/p>\n<p align=\"justify\">\u201cExiting the third quarter, ZEJULA achieved 60% market share of the ovarian cancer patient population treated with a PARP inhibitor. This is a result of our team\u2019s solid execution, and is supported by the feedback from physicians and patients, which continues to be excellent with regards to the benefit ZEJULA provides for women living with ovarian cancer,\u201d said Lonnie Moulder, CEO of TESARO. \u201cLooking ahead, we are actively preparing for two additional product launches in 2017 \u2014 ZEJULA in Europe and VARUBI IV in the U.S. \u2014 and expanding our niraparib development programs to broaden its use with the PRIMA Phase 3 first line ovarian cancer study and the initiation of multiple combination studies in ovarian, lung, and breast cancer. We are rapidly advancing our pipeline of immuno-oncology candidates with three antibodies now in the clinic, and we are excited about the potential for the combination of TSR-022 and TSR-042 to meaningfully benefit patients with advanced solid tumors.\u201d<\/p>\n<p align=\"justify\"><strong>Recent Business Highlights<\/strong><\/p>\n<ul type=\"disc\">\n<li>On October 25, 2017, the U.S. Food and Drug Administration (FDA) approved the intravenous (IV) formulation of VARUBI<sup>\u00ae <\/sup>(rolapitant), and the U.S. commercial launch is planned for November. The unit demand for VARUBI oral capsules increased 74% for Q3 2017 vs. Q3 2016, as the brand continues to penetrate the U.S. oral NK-1 market.<\/li>\n<li>ZEJULA<sup>\u00ae<\/sup> (niraparib) is the most prescribed PARP inhibitor in the U.S., with approximately 2,500 patients treated during the month of September.<\/li>\n<li>The European Medicines Agency\u2019s (EMA) Committee for Medicinal Products for Human Use (CHMP) issued a positive opinion for ZEJULA as a monotherapy for the maintenance treatment of adult patients with platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete response (CR) or partial response (PR) to platinum-based chemotherapy.<\/li>\n<li>Pre-launch preparations continue in support of a European launch of ZEJULA by year-end 2017 beginning with Germany, pending European Commission approval.<\/li>\n<li>The niraparib expanded access program (EAP) in Europe has enrolled more than 350 patients to date.<\/li>\n<li>Clinical trials were initiated to support planned Phase 3 studies of niraparib combined with our anti-PD-1 antibody, TSR-042, in patients with lung and ovarian cancers and to evaluate niraparib plus TSR-042 in patients with advanced or metastatic cancers suitable for treatment with an anti-PD-1 antibody, including ovarian and lung.<\/li>\n<li>Enrollment continues in the PRIMA trial of niraparib for patients with first-line ovarian cancer and the QUADRA trial of niraparib for the treatment of patients with ovarian cancer who have received three or more prior lines of chemotherapy.<\/li>\n<li>The Phase 2 TOPACIO trial of niraparib plus pembrolizumab is ongoing with additional data expected in 1H 2018. Preliminary Phase 2 data presented at ESMO showed activity in patients with platinum-resistant ovarian cancer and patients with triple-negative breast cancer.<\/li>\n<li>The Janssen GALAHAD Phase 2 efficacy and safety study of niraparib in men with metastatic castration-resistant prostate cancer and DNA-repair anomalies is ongoing to support a planned regulatory submission in 2019.<\/li>\n<li>Phase 1 data for TSR-042 (anti-PD-1 antibody) presented at ESMO demonstrated a predictable safety profile and clinical activity in heavily pre-treated patients. The GARNET registration trial of TSR-042 continues to enroll patients with metastatic microsatellite instability-high (MSI-H) cancers.<\/li>\n<li>To support initiation of planned Phase 3 studies, a clinical study was initiated to evaluate TSR-042 in combination with carboplatin-paclitaxel in patients with advanced or metastatic cancer.<\/li>\n<li>Enrollment continues in the Phase 1 AMBER combination study of TSR-022 (anti-TIM-3 antibody) plus TSR-042, and the Phase 1 CITRINO dose-escalation trial of TSR-033 (anti-LAG-3 antibody). Data from the monotherapy, dose-escalation portion of the AMBER trial of TSR-022 will be presented at the Society for Immunotherapy of Cancer (SITC) annual meeting on November 10.<\/li>\n<\/ul>\n<p align=\"justify\"><strong>Third Quarter 2017 Financial Results<\/strong><\/p>\n<p align=\"justify\">TESARO reported total revenue of $142.8 million for the third quarter of 2017, compared to $17.0 million for the third quarter of 2016.<\/p>\n<p align=\"justify\">Net product revenue totaled $41.8 million for the third quarter of 2017, which included ZEJULA revenues of $39.4 million and VARUBI\/VARUBY revenues of $2.4 million. This compares to net product revenue of $1.3 million for the third quarter of 2016.<\/p>\n<p align=\"justify\">License, collaboration, and other revenue totaled $101.0 million for the third quarter of 2017 and included the $100.0 million up-front payment received as part of the license agreement with Takeda. This compares to license, collaboration, and other revenue of $15.7 million for the third quarter of 2016, which included the majority of the $15.0 million up-front payment received as part of the Zai Lab license agreement.<\/p>\n<p align=\"justify\">Cost of sales totaled $7.5 million for the third quarter of 2017 and included $6.2 million associated with product revenue and $1.3 million related to amortization of milestones recorded upon FDA approval of ZEJULA and first commercial sales of VARUBI\/VARUBY in the U.S. and Europe. Cost of sales totaled $0.8 million for the third quarter of 2016.<\/p>\n<p align=\"justify\">Research and development expenses increased to $73.4 million for the third quarter of 2017, compared to $60.8 million for the third quarter of 2016, driven primarily by increased headcount, the advancement of our earlier-stage immuno-oncology portfolio, and expansion of the TSR-042 and TSR-022 programs.<\/p>\n<p align=\"justify\">Selling, general and administrative expenses increased to $84.0 million for the third quarter of 2017, compared to $37.7 million for the third quarter of 2016, primarily due to increased headcount, activities in support of the launches of ZEJULA and VARUBY in the U.S. and Europe, and higher professional service fees.<\/p>\n<p align=\"justify\">Operating expenses as described above include total non-cash, stock-based compensation expense of $25.0 million for the third quarter of 2017, compared to $12.9 million for the third quarter of 2016.<\/p>\n<p align=\"justify\">Net loss totaled $25.3 million, or ($0.47) per share, for the third quarter of 2017, compared to a net loss of $87.9 million, or ($1.72) per share, for the third quarter of 2016.<\/p>\n<p align=\"justify\">As of September 30, 2017, TESARO had approximately $521.3 million in cash and cash equivalents and approximately 54.4 million outstanding shares of common stock.<\/p>\n<p><strong>Corporate Objectives<\/strong><\/p>\n<p align=\"justify\">TESARO intends to achieve the following key objectives:<\/p>\n<p>Commercial Products:<\/p>\n<ul type=\"disc\">\n<li>Continue to execute on the ongoing U.S. launch of ZEJULA and solidify its position as the market-leading PARP inhibitor for patients with recurrent ovarian cancer;<\/li>\n<li>Launch ZEJULA in Europe by year-end 2017, pending European Commission approval; and<\/li>\n<li>Launch VARUBI IV in the U.S.<\/li>\n<\/ul>\n<p align=\"justify\">Pipeline Candidates:<\/p>\n<ul type=\"disc\">\n<li>Rapidly advance the GARNET registration trial of TSR-042 in MSI-H cancers, with the intent of supporting accelerated FDA approval;<\/li>\n<li>Define the registration path in platinum-resistant ovarian cancer and triple negative breast cancer in Q1 2018, pending data from TOPACIO trial;<\/li>\n<li>Report initial data for the AMBER trial of TSR-022 in combination with TSR-042 in 2018;<\/li>\n<li>Complete the dose escalation phase of the TSR-033 CITRINO trial and in early 2018 initiate a combination trial of TSR-033 plus TSR-042;<\/li>\n<li>Initiate OVARIO, a Phase 2 clinical trial of niraparib in combination with bevacizumab in patients with first-line ovarian cancer by year end;<\/li>\n<li>Initiate a Phase 3 clinical trial of niraparib in combination with TSR-042 in first-line ovarian cancer in 1H 2018; and<\/li>\n<li>Initiate a Phase 3 clinical trial of niraparib in combination with TSR-042 in NSCLC in 2H 2018.<\/li>\n<\/ul>\n<p align=\"justify\"><strong>Today&#8217;s Conference Call and Webcast<br \/><\/strong>TESARO will host a conference call to discuss the Company&#8217;s third quarter operating results and provide an update on the Company&#8217;s commercial products and development programs today at 4:15 P.M. Eastern time. The accompanying slide presentation and live webcast of the conference call can be accessed by visiting the TESARO website at www.tesarobio.com. The call can be accessed by dialing (877) 853-5334 (U.S. and Canada) or (970) 315-0307 (international). A replay of the webcast will be archived on the Company&#8217;s website for 30 days following the call.<\/p>\n<p align=\"justify\"><strong>About ZEJULA (Niraparib)<br \/><\/strong>ZEJULA (niraparib) is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.\u00a0 In preclinical studies, ZEJULA concentrates in the tumor relative to plasma, delivering greater than 90% durable inhibition of PARP 1\/2 and a persistent antitumor effect. Myelodysplastic Syndrome\/Acute Myeloid Leukemia (MDS\/AML), including some fatal cases, was reported in patients treated with ZEJULA. Discontinue ZEJULA if MDS\/AML is confirmed.\u00a0 Hematologic adverse reactions (thrombocytopenia, anemia and neutropenia), as well as cardiovascular effects (hypertension and hypertensive crisis) have been reported in patients treated with ZEJULA. Monitor complete blood counts to detect hematologic adverse reactions, as well as to detect cardiovascular disorders, during treatment.\u00a0 ZEJULA can cause fetal harm and females of reproductive potential should use effective contraception. Please see full prescribing information, including additional important safety information, available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=aArgl-ZGWfgMNwNH10iUkBFvfm1rb9DHXZEnKrc8bayTbVLqsuEvM8t4fKz51Z7y48f0gVNNdd5ArAmTybSGnQ==\" rel=\"nofollow\"  title=\"www.zejula.com\">www.zejula.com<\/a>.<\/p>\n<p align=\"justify\"><strong>About VARUBI<sup>\u00ae<\/sup> (rolapitant)<\/strong><br \/>VARUBI is a substance P\/neurokinin-1 (NK-1) receptor antagonist indicated in combination with other antiemetic agents in adults for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including, but not limited to, highly emetogenic chemotherapy. NK-1 receptors are highly concentrated in the brain and bind neurokinin substance P.\u00a0 Activation of NK-1 receptors plays a central role in nausea and vomiting induced by emetogenic stimuli, including certain cancer chemotherapies.\u00a0 A Positron Emission Tomography (PET) study with rolapitant in normal, healthy volunteers demonstrated that rolapitant crosses the blood brain barrier and occupies brain NK-1 receptors at high levels for up to 120 hours. VARUBI has a half-life of approximately seven days, which may contribute to the ability of a single dose of VARUBI to cover the entire delayed CINV Phase (25-120 hours).\u00a0 VARUBI is contraindicated in patients taking CYP2D6 substrates with a narrow therapeutic index, such as thioridazine and pimozide. VARUBI can significantly increase the plasma concentrations of thioridazine and pimozide, which may result in QT prolongation and Torsades de Pointes. VARUBI is a moderate inhibitor of CYP2D6 and significantly increases the plasma concentrations of CYP2D6 substrates for at least 28 days, with inhibitory effects expected to persist for an unknown duration.\u00a0 Monitor for adverse reactions when VARUBI is co-administered with CYP2D6 substrates without a narrow therapeutic index (avoid co-administration with CYP2D6 substrates with a narrow therapeutic index, thioridazine and pimozide; see Contraindication).\u00a0 In clinical trials, the most common adverse reactions reported were neutropenia, hiccups, decreased appetite and dizziness.\u00a0 IV administration of VARUBI was also associated with infusion-related symptoms (e.g., sensation of warmth, abdominal pain, dizziness, and paresthesia). Avoid use of VARUBI in patients who require chronic administration of strong CYP3A4 inducers (e.g., rifampin), as significantly reduced plasma concentrations of VARUBI can decrease the efficacy of VARUBI. Oral VARUBI is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp).\u00a0 Increased plasma concentrations of BCRP substrates (e.g., methotrexate, topotecan, or irinotecan) and P-gp substrates (e.g., digoxin) with a narrow therapeutic index may result in potential adverse reactions. Monitor digoxin concentrations with concomitant use of VARUBI, and adjust the dosage as needed to maintain therapeutic concentrations. Monitor INR and prothrombin time and adjust the dosage of warfarin, as needed, to maintain target INR. VARUBI is available by prescription only. Please see full prescribing information, including additional important safety information, available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=z2FnuviSrlzxmgm0Zsu9Muuj8MCf8Ex3gWeEpR3NrTLTy3C1kIYyiu3IsxwU9XlblCcfbo0GkCGbr_cQMSo9QQ==\" rel=\"nofollow\"  title=\"www.varubirx.com\">www.varubirx.com<\/a>.<\/p>\n<p align=\"justify\"><strong>About TESARO<br \/><\/strong>TESARO is an oncology-focused biopharmaceutical company devoted to providing transformative therapies to people bravely facing cancer. For more information, visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ZsTlvzJyGf9fxqmwbWmUkyJuFOWaR37-RdwbDdon08DfOQLU1pwtxco1dqVadG4eKBsy2w3bnpZ1A9lZGR_VtTbtj1df3-3QQRF6lVBEpQE=\" rel=\"nofollow\"  title=\"www.tesarobio.com\">www.tesarobio.com<\/a>, and follow us on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TKuzAPAtVOcvS7XHYHtKP8zSHs4oOrs8SNsuULjEll-4HQyVLvVoZdusUbGGnKjGfY7WhqdAhfxw41I93Xn67A==\" rel=\"nofollow\"  title=\"Twitter\">Twitter<\/a> and <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=93W24pycO4uV7qG9EHkzYK8590-_BpYufe7t2AwB-WifaeG0sfE4-BTQHUu-uo3Ym4W70JwD3xzfPcDuv7rMnoEt6un5fwgHO_FJDArlIic=\" rel=\"nofollow\"  title=\"LinkedIn\">LinkedIn<\/a>.<\/p>\n<p align=\"justify\"><strong>TESARO Contacts:<br \/><\/strong>Jennifer Davis<br \/>Vice President, Corporate Communications &amp; Investor Relations<br \/>+1.781.325.1116 or <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=V7rt7tqfg4peTDokKdxcW3V70eQFuz112183UBk9RTn47Gq_YehYzyYMBsKuI-anbYmKkZj9Fj_jMiY8u0f25IJgj63OG25CgwDYKNoTG8I=\" rel=\"nofollow\"  title=\"jdavis@tesarobio.com\">jdavis@tesarobio.com<\/a><\/p>\n<p align=\"justify\">Kate Rausch<br \/>Associate Director, Investor Relations<br \/>+1.781.257.2505 or <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fXNy6DSaL7FeMUpZ7viXQd3gSs4EHfJs7v8dAiIZj--ngkdw2W1OSkwA6WL0BEhDeLa6SkDEW5xiRY67XghfvrJOHw-Dqk5LoBUj_QPsSIE=\" rel=\"nofollow\"  title=\"krausch@tesarobio.com\">krausch@tesarobio.com<\/a><\/p>\n<p align=\"justify\"><strong>Forward Looking Statements<br \/><\/strong><em>To the extent that statements contained in this press release are not descriptions of historical facts regarding TESARO, they are forward-looking statements reflecting the current beliefs and expectations of management made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Words such as &#8220;may,&#8221; &#8220;will,&#8221; &#8220;expect,&#8221; &#8220;anticipate,&#8221; &#8220;estimate,&#8221; &#8220;intend,&#8221; and similar expressions (as well as other words or expressions referencing future events, conditions, or circumstances) are intended to identify forward-looking statements. Examples of forward-looking statements contained in this press release include, among others, statements regarding the expected timing of the launch of VARUBI IV in the U.S., the expected timing of our planned commercial launch of ZEJULA in Europe, the design and expected timing of initiation and data from our various ongoing and planned niraparib, TSR-042, TSR-033, TSR-022, combination, and other clinical trials, and our expectation to achieve our various key corporate objectives. Forward-looking statements in this release involve substantial risks and uncertainties that could cause our research and pre-clinical development programs, clinical development programs, future results, performance, or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others risks related to competition, the uncertainties inherent in the execution and completion of clinical trials, uncertainties surrounding the timing of availability of data from clinical trials, uncertainties surrounding our ongoing discussions with and potential actions by regulatory authorities, uncertainties regarding regulatory approvals, uncertainties regarding certain expenditures, risks related to manufacturing and supply, risks related to intellectual property, and other matters that could affect the availability or commercial potential of our products and drug candidates. TESARO undertakes no obligation to update or revise any forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the Company in general, see TESARO&#8217;s Annual Report on Form 10-K for the year ended December 31, 2016, and Quarterly Report on Form 10-Q for the quarter ended June 30, 2017.<\/em><\/p>\n<p align=\"justify\" \/>\n<table class=\"gnw_table_border_collapse gnw_table_border_collapse hugin\" style=\"width:100%;\">\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"17\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"17\"><strong>TESARO, Inc.<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"17\"><strong>Unaudited Condensed Consolidated Statements of Operations<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"17\">(in thousands, except per share amounts)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"7\"><strong>Three Months Ended<\/strong><br \/><strong> September 30,<\/strong><\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"7\"><strong>Nine Months Ended<\/strong><br \/><strong> September 30,<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\"><strong>2016<\/strong><\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\"><strong>2017<\/strong><\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\"><strong>2016<\/strong><\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_vertical_align_bottom hugin gnw_align_center\"><strong>2017<\/strong><\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_vertical_align_bottom hugin gnw_align_center\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"3\">(as revised)(1)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"3\">(as revised)(1)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Revenues:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Product revenue, net:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i30 hugin\">ZEJULA<sup>\u00ae\u00a0<\/sup><\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 &#8211;<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 39,375<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 &#8211;<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 65,321<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i30 hugin\">VARUBI<sup>\u00ae<\/sup>\/VARUBY<sup>\u00ae<\/sup>\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,326<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,380<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,844<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 7,402<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Total product revenue, net<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,326<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 41,755<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,844<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 72,723<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">License, collaboration and other revenues<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 15,661<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 101,011<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 50,253<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 102,580<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Total revenues<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 16,987<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 142,766<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 53,097<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 175,303<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Expenses:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Cost of sales &#8211; product<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 378<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 6,216<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 691<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 10,280<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Cost of sales &#8211; intangible asset amortization<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 464<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,254<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,391<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 4,723<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Research and development (2)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 60,783<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 73,388<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 163,630<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 210,910<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Selling, general and administrative (2)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 37,685<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 83,998<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 104,052<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 246,239<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Acquired in-process research and development<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,940<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 &#8211;<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 9,940<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 7,000<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Total expenses<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 101,250<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 164,856<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 279,704<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 479,152<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Loss from operations<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (84,263<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (22,090<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (226,607<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (303,849<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Interest and other income (expense), net<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (3,587<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (3,048<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (11,377<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (9,941<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Loss before income taxes<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (87,850<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (25,138<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (237,984<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (313,790<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Provision for income taxes<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 &#8211;<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 139<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 &#8211;<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 271<\/td>\n<td class=\"gnw_border_bottom_solid gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Net loss<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (87,850<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (25,277<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (237,984<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (314,061<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Net loss per share applicable to<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">common stockholders &#8211; basic and diluted<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (1.72<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (0.47<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (5.17<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 (5.82<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Weighted-average number of common<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">shares used in net loss per share applicable<br \/> to common stockholders &#8211; basic and diluted<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 51,151<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 54,241<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 45,994<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 53,971<\/td>\n<td class=\"gnw_border_bottom_double gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_border_top_solid gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"17\">(1) The Company adopted Financial Accounting Standards Board Accounting Standards Update No. 2014-09 effective January 1, 2017,<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"17\">with full retrospective application to January 1, 2015.\u00a0 Results for periods prior to January 1, 2017 have been revised accordingly.<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"9\">(2) Expenses include the following amounts of non-cash stock-based compensation expense:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Research and development<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 5,605<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 8,545<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 13,826<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 23,532<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Selling, general and administrative<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 7,314<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 16,471<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 20,238<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 43,393<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_left gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p><em>\u00a0<\/em><\/p>\n<table class=\"gnw_table_border_collapse gnw_table_border_collapse hugin\" style=\"width:100%;\">\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"11\"><strong>TESARO, Inc.<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"11\"><strong>Unaudited Condensed Consolidated Balance Sheets<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"11\">(in thousands)<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"2\"><strong>December 31,<\/strong><br \/><strong> 2016<\/strong><\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_bottom_solid gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"2\"><strong>September 30,<\/strong><br \/><strong> 2017<\/strong><\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"2\">(as revised)(1)<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\"><strong>Assets<\/strong><\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_align_center gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Current assets:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"3\">Cash and cash equivalents<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 785,877<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 521,265<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Accounts receivable<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 6,195<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 27,680<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\">Inventories<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 14,700<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 50,527<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Other current assets<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 10,515<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 22,257<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Total current assets<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 817,287<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 621,729<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Intangible assets, net<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 12,877<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 43,155<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">Property and equipment, net<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 6,640<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 9,877<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Restricted cash<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 1,694<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,521<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">Other assets<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 3,795<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 8,436<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Total assets<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 842,293<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 685,718<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"4\"><strong>Liabilities and stockholders&#8217; equity<\/strong><\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Current liabilities:<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Accounts payable<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 5,236<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 5,984<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Accrued expenses<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 68,700<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 123,076<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"3\">Deferred revenue, current<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 95<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 95<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Other current liabilities<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,978<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 2,287<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Total current liabilities<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 77,009<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 131,442<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Convertible notes, net<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 131,775<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 140,362<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">Deferred revenue, non-current<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 305<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 235<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"3\">Other non-current liabilities<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 5,086<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 6,318<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"2\">Total liabilities<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 214,175<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 278,357<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">Total stockholders&#8217; equity<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 628,118<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 407,361<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom gnw_label_i20 hugin\" colspan=\"4\">Total liabilities and stockholders&#8217; equity<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 842,293<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_right_none gnw_align_right gnw_vertical_align_bottom hugin\">$<\/td>\n<td class=\"gnw_border_top_solid gnw_border_bottom_double gnw_padding_left_none gnw_align_right gnw_vertical_align_bottom hugin\">\u00a0 685,718<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"5\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"11\">(1) The Company adopted Financial Accounting Standards Board Accounting Standards<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"11\">Update No. 2014-09 effective January 1, 2017, with full retrospective application to January 1,<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"9\">2015.\u00a0 Results for periods prior to January 1, 2017 have been revised accordingly.<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<tr>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"5\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\">\u00a0<\/td>\n<td class=\"gnw_vertical_align_bottom hugin\" colspan=\"2\">\u00a0<\/td>\n<\/tr>\n<\/table>\n<p><\/p>\n<p \/>\n","protected":false},"excerpt":{"rendered":"<ul>\n<li><strong>ZEJULA<sup>&reg;<\/sup> was the most prescribed PARP inhibitor in U.S. with Q3 net sales of $39.4 million<\/strong><\/li>\n<li><strong>Positive CHMP opinion issued for ZEJULA in E.U.; commercial launch anticipated to begin by year-end<\/strong><\/li>\n<li><strong>Expansion of niraparib development program underway for multiple tumor types<\/strong><\/li>\n<li><strong>VARUBI<sup>&reg;<\/sup> IV approved by U.S. FDA; commercial launch planned for November<\/strong><\/li>\n<li><strong>Phase 1 combination study of TSR-022 (anti-TIM-3) and TSR-042 (anti-PD-1) now enrolling patients<\/strong><\/li>\n<li><strong>Phase 1 study of TSR-033 (anti-LAG-3) now enrolling patients<\/strong><\/li>\n<\/ul>\n<p class=\"small\" align=\"justify\">WALTHAM, Mass., Nov.  07, 2017  (GLOBE NEWSWIRE) &#8212; TESARO, Inc. (NASDAQ:<a href=\"http:\/\/globenewswire.com\/News\/Listing?symbol=TSRO&amp;exchange=2\">TSRO<\/a>), an oncology-focused biopharmaceutical company, today reported operating results for third-quarter 2017 and provided an update on the Company&#8217;s commercial products and development programs.<\/p>\n<p class=\"small\" align=\"justify\">&ldquo;Exiting the third quarter, ZEJULA achieved 60% market share of the ovarian cancer patient population treated with a PARP inhibitor. This is a result of our team&rsquo;s solid execution, and is supported by the feedback from physicians and patients, which continues to be excellent with regards to the benefit ZEJULA provides for women living with ovarian cancer,&rdquo; said Lonnie Moulder, CEO of TESARO. &ldquo;Looking ahead, we are actively preparing for two additional product launches in 2017 &mdash; ZEJULA in Europe and VARUBI IV in the U.S. &mdash; and expanding our niraparib development programs to broaden its use with the PRIMA Phase 3 first line ovarian cancer study and the initiation of multiple combination studies in ovarian, lung, and breast cancer. We are rapidly advancing our pipeline of immuno-oncology candidates with three antibodies now in the clinic, and we are excited about the potential for the combination of TSR-022 and TSR-042 to meaningfully benefit patients with advanced solid tumors.&rdquo;<\/p>\n<p class=\"small\" align=\"justify\"><strong>Recent Business Highlights<\/strong><\/p>\n<ul type=\"disc\">\n<li>On October 25, 2017, the U.S. Food and Drug Administration (FDA) approved the intravenous (IV) formulation of VARUBI<sup>&reg; <\/sup>(rolapitant), and the U.S. commercial launch is planned for November. The unit demand for VARUBI oral capsules increased 74% for Q3 2017 vs. Q3 2016, as the brand continues to penetrate the U.S. oral NK-1 market.<\/li>\n<li>ZEJULA<sup>&reg;<\/sup> (niraparib) is the most prescribed PARP inhibitor in the U.S., with approximately 2,500 patients treated during the month of September.<\/li>\n<li>The European Medicines Agency&rsquo;s (EMA) Committee for Medicinal Products for Human Use (CHMP) issued a positive opinion for ZEJULA as a monotherapy for the maintenance treatment of adult patients with platinum-sensitive relapsed high grade serous epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete response (CR) or partial response (PR) to platinum-based chemotherapy.<\/li>\n<li>Pre-launch preparations continue in support of a European launch of ZEJULA by year-end 2017 beginning with Germany, pending European Commission approval.<\/li>\n<li>The niraparib expanded access program (EAP) in Europe has enrolled more than 350 patients to date.<\/li>\n<li>Clinical trials were initiated to support planned Phase 3 studies of niraparib combined with our anti-PD-1 antibody, TSR-042, in patients with lung and ovarian cancers and to evaluate niraparib plus TSR-042 in patients with advanced or metastatic cancers suitable for treatment with an anti-PD-1 antibody, including ovarian and lung.<\/li>\n<li>Enrollment continues in the PRIMA trial of niraparib for patients with first-line ovarian cancer and the QUADRA trial of niraparib for the treatment of patients with ovarian cancer who have received three or more prior lines of chemotherapy.<\/li>\n<li>The Phase 2 TOPACIO trial of niraparib plus pembrolizumab is ongoing with additional data expected in 1H 2018. Preliminary Phase 2 data presented at ESMO showed activity in patients with platinum-resistant ovarian cancer and patients with triple-negative breast cancer.<\/li>\n<li>The Janssen GALAHAD Phase 2 efficacy and safety study of niraparib in men with metastatic castration-resistant prostate cancer and DNA-repair anomalies is ongoing to support a planned regulatory submission in 2019.<\/li>\n<li>Phase 1 data for TSR-042 (anti-PD-1 antibody) presented at ESMO demonstrated a predictable safety profile and clinical activity in heavily pre-treated patients. The GARNET registration trial of TSR-042 continues to enroll patients with metastatic microsatellite instability-high (MSI-H) cancers.<\/li>\n<li>To support initiation of planned Phase 3 studies, a clinical study was initiated to evaluate TSR-042 in combination with carboplatin-paclitaxel in patients with advanced or metastatic cancer.<\/li>\n<li>Enrollment continues in the Phase 1 AMBER combination study of TSR-022 (anti-TIM-3 antibody) plus TSR-042, and the Phase 1 CITRINO dose-escalation trial of TSR-033 (anti-LAG-3 antibody). Data from the monotherapy, dose-escalation portion of the AMBER trial of TSR-022 will be presented at the Society for Immunotherapy of Cancer (SITC) annual meeting on November 10.<\/li>\n<\/ul>\n<p class=\"small\" align=\"justify\"><strong>Third Quarter 2017 Financial Results<\/strong><\/p>\n<p class=\"small\" align=\"justify\">TESARO reported total revenue of $142.8 million for the third quarter of 2017, compared to $17.0 million for the third quarter of 2016.<\/p>\n<p class=\"small\" align=\"justify\">Net product revenue totaled $41.8 million for the third quarter of 2017, which included ZEJULA revenues of $39.4 million and VARUBI\/VARUBY revenues of $2.4 million. This compares to net product revenue of $1.3 million for the third quarter of 2016.<\/p>\n<p class=\"small\" align=\"justify\">License, collaboration, and other revenue totaled $101.0 million for the third quarter of 2017 and included the $100.0 million up-front payment received as part of the license agreement with Takeda. This compares to license, collaboration, and other revenue of $15.7 million for the third quarter of 2016, which included the majority of the $15.0 million up-front payment received as part of the Zai Lab license agreement.<\/p>\n<p class=\"small\" align=\"justify\">Cost of sales totaled $7.5 million for the third quarter of 2017 and included $6.2 million associated with product revenue and $1.3 million related to amortization of milestones recorded upon FDA approval of ZEJULA and first commercial sales of VARUBI\/VARUBY in the U.S. and Europe. Cost of sales totaled $0.8 million for the third quarter of 2016.<\/p>\n<p class=\"small\" align=\"justify\">Research and development expenses increased to $73.4 million for the third quarter of 2017, compared to $60.8 million for the third quarter of 2016, driven primarily by increased headcount, the advancement of our earlier-stage immuno-oncology portfolio, and expansion of the TSR-042 and TSR-022 programs.<\/p>\n<p class=\"small\" align=\"justify\">Selling, general and administrative expenses increased to $84.0 million for the third quarter of 2017, compared to $37.7 million for the third quarter of 2016, primarily due to increased headcount, activities in support of the launches of ZEJULA and VARUBY in the U.S. and Europe, and higher professional service fees.<\/p>\n<p class=\"small\" align=\"justify\">Operating expenses as described above include total non-cash, stock-based compensation expense of $25.0 million for the third quarter of 2017, compared to $12.9 million for the third quarter of 2016.<\/p>\n<p class=\"small\" align=\"justify\">Net loss totaled $25.3 million, or ($0.47) per share, for the third quarter of 2017, compared to a net loss of $87.9 million, or ($1.72) per share, for the third quarter of 2016.<\/p>\n<p class=\"small\" align=\"justify\">As of September 30, 2017, TESARO had approximately $521.3 million in cash and cash equivalents and approximately 54.4 million outstanding shares of common stock.<\/p>\n<p class=\"small\"><strong>Corporate Objectives<\/strong><\/p>\n<p class=\"small\" align=\"justify\">TESARO intends to achieve the following key objectives:<\/p>\n<p class=\"small\">Commercial Products:<\/p>\n<ul type=\"disc\">\n<li>Continue to execute on the ongoing U.S. launch of ZEJULA and solidify its position as the market-leading PARP inhibitor for patients with recurrent ovarian cancer;<\/li>\n<li>Launch ZEJULA in Europe by year-end 2017, pending European Commission approval; and<\/li>\n<li>Launch VARUBI IV in the U.S.<\/li>\n<\/ul>\n<p class=\"small\" align=\"justify\">Pipeline Candidates:<\/p>\n<ul type=\"disc\">\n<li>Rapidly advance the GARNET registration trial of TSR-042 in MSI-H cancers, with the intent of supporting accelerated FDA approval;<\/li>\n<li>Define the registration path in platinum-resistant ovarian cancer and triple negative breast cancer in Q1 2018, pending data from TOPACIO trial;<\/li>\n<li>Report initial data for the AMBER trial of TSR-022 in combination with TSR-042 in 2018;<\/li>\n<li>Complete the dose escalation phase of the TSR-033 CITRINO trial and in early 2018 initiate a combination trial of TSR-033 plus TSR-042;<\/li>\n<li>Initiate OVARIO, a Phase 2 clinical trial of niraparib in combination with bevacizumab in patients with first-line ovarian cancer by year end;<\/li>\n<li>Initiate a Phase 3 clinical trial of niraparib in combination with TSR-042 in first-line ovarian cancer in 1H 2018; and<\/li>\n<li>Initiate a Phase 3 clinical trial of niraparib in combination with TSR-042 in NSCLC in 2H 2018.<\/li>\n<\/ul>\n<p class=\"small\" align=\"justify\"><strong>Today&#8217;s Conference Call and Webcast<br \/><\/strong>TESARO will host a conference call to discuss the Company&#8217;s third quarter operating results and provide an update on the Company&#8217;s commercial products and development programs today at 4:15 P.M. Eastern time. The accompanying slide presentation and live webcast of the conference call can be accessed by visiting the TESARO website at www.tesarobio.com. The call can be accessed by dialing (877) 853-5334 (U.S. and Canada) or (970) 315-0307 (international). A replay of the webcast will be archived on the Company&#8217;s website for 30 days following the call.<\/p>\n<p class=\"small\" align=\"justify\"><strong>About ZEJULA (Niraparib)<br \/><\/strong>ZEJULA (niraparib) is a poly (ADP-ribose) polymerase (PARP) inhibitor indicated for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.&nbsp; In preclinical studies, ZEJULA concentrates in the tumor relative to plasma, delivering greater than 90% durable inhibition of PARP 1\/2 and a persistent antitumor effect. Myelodysplastic Syndrome\/Acute Myeloid Leukemia (MDS\/AML), including some fatal cases, was reported in patients treated with ZEJULA. Discontinue ZEJULA if MDS\/AML is confirmed.&nbsp; Hematologic adverse reactions (thrombocytopenia, anemia and neutropenia), as well as cardiovascular effects (hypertension and hypertensive crisis) have been reported in patients treated with ZEJULA. Monitor complete blood counts to detect hematologic adverse reactions, as well as to detect cardiovascular disorders, during treatment.&nbsp; ZEJULA can cause fetal harm and females of reproductive potential should use effective contraception. Please see full prescribing information, including additional important safety information, available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=aArgl-ZGWfgMNwNH10iUkBFvfm1rb9DHXZEnKrc8bayTbVLqsuEvM8t4fKz51Z7y48f0gVNNdd5ArAmTybSGnQ==\" rel=\"nofollow\" target=\"_blank\" title=\"www.zejula.com\">www.zejula.com<\/a>.<\/p>\n<p class=\"small\" align=\"justify\"><strong>About VARUBI<sup>&reg;<\/sup> (rolapitant)<\/strong><br \/>VARUBI is a substance P\/neurokinin-1 (NK-1) receptor antagonist indicated in combination with other antiemetic agents in adults for the prevention of delayed nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, including, but not limited to, highly emetogenic chemotherapy. NK-1 receptors are highly concentrated in the brain and bind neurokinin substance P.&nbsp; Activation of NK-1 receptors plays a central role in nausea and vomiting induced by emetogenic stimuli, including certain cancer chemotherapies.&nbsp; A Positron Emission Tomography (PET) study with rolapitant in normal, healthy volunteers demonstrated that rolapitant crosses the blood brain barrier and occupies brain NK-1 receptors at high levels for up to 120 hours. VARUBI has a half-life of approximately seven days, which may contribute to the ability of a single dose of VARUBI to cover the entire delayed CINV Phase (25-120 hours).&nbsp; VARUBI is contraindicated in patients taking CYP2D6 substrates with a narrow therapeutic index, such as thioridazine and pimozide. VARUBI can significantly increase the plasma concentrations of thioridazine and pimozide, which may result in QT prolongation and Torsades de Pointes. VARUBI is a moderate inhibitor of CYP2D6 and significantly increases the plasma concentrations of CYP2D6 substrates for at least 28 days, with inhibitory effects expected to persist for an unknown duration.&nbsp; Monitor for adverse reactions when VARUBI is co-administered with CYP2D6 substrates without a narrow therapeutic index (avoid co-administration with CYP2D6 substrates with a narrow therapeutic index, thioridazine and pimozide; see Contraindication).&nbsp; In clinical trials, the most common adverse reactions reported were neutropenia, hiccups, decreased appetite and dizziness.&nbsp; IV administration of VARUBI was also associated with infusion-related symptoms (e.g., sensation of warmth, abdominal pain, dizziness, and paresthesia). Avoid use of VARUBI in patients who require chronic administration of strong CYP3A4 inducers (e.g., rifampin), as significantly reduced plasma concentrations of VARUBI can decrease the efficacy of VARUBI. Oral VARUBI is an inhibitor of breast cancer resistance protein (BCRP) and P-glycoprotein (P-gp).&nbsp; Increased plasma concentrations of BCRP substrates (e.g., methotrexate, topotecan, or irinotecan) and P-gp substrates (e.g., digoxin) with a narrow therapeutic index may result in potential adverse reactions. Monitor digoxin concentrations with concomitant use of VARUBI, and adjust the dosage as needed to maintain therapeutic concentrations. Monitor INR and prothrombin time and adjust the dosage of warfarin, as needed, to maintain target INR. VARUBI is available by prescription only. Please see full prescribing information, including additional important safety information, available at <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=z2FnuviSrlzxmgm0Zsu9Muuj8MCf8Ex3gWeEpR3NrTLTy3C1kIYyiu3IsxwU9XlblCcfbo0GkCGbr_cQMSo9QQ==\" rel=\"nofollow\" target=\"_blank\" title=\"www.varubirx.com\">www.varubirx.com<\/a>.<\/p>\n<p class=\"small\" align=\"justify\"><strong>About TESARO<br \/><\/strong>TESARO is an oncology-focused biopharmaceutical company devoted to providing transformative therapies to people bravely facing cancer. For more information, visit <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=ZsTlvzJyGf9fxqmwbWmUkyJuFOWaR37-RdwbDdon08DfOQLU1pwtxco1dqVadG4eKBsy2w3bnpZ1A9lZGR_VtTbtj1df3-3QQRF6lVBEpQE=\" rel=\"nofollow\" target=\"_blank\" title=\"www.tesarobio.com\">www.tesarobio.com<\/a>, and follow us on <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=TKuzAPAtVOcvS7XHYHtKP8zSHs4oOrs8SNsuULjEll-4HQyVLvVoZdusUbGGnKjGfY7WhqdAhfxw41I93Xn67A==\" rel=\"nofollow\" target=\"_blank\" title=\"Twitter\">Twitter<\/a> and <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=93W24pycO4uV7qG9EHkzYK8590-_BpYufe7t2AwB-WifaeG0sfE4-BTQHUu-uo3Ym4W70JwD3xzfPcDuv7rMnoEt6un5fwgHO_FJDArlIic=\" rel=\"nofollow\" target=\"_blank\" title=\"LinkedIn\">LinkedIn<\/a>.<\/p>\n<p class=\"small\" align=\"justify\"><strong>TESARO Contacts:<br \/><\/strong>Jennifer Davis<br \/>Vice President, Corporate Communications &amp; Investor Relations<br \/>+1.781.325.1116 or <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=V7rt7tqfg4peTDokKdxcW3V70eQFuz112183UBk9RTn47Gq_YehYzyYMBsKuI-anbYmKkZj9Fj_jMiY8u0f25IJgj63OG25CgwDYKNoTG8I=\" rel=\"nofollow\" target=\"_blank\" title=\"jdavis@tesarobio.com\">jdavis@tesarobio.com<\/a><\/p>\n<p class=\"small\" align=\"justify\">Kate Rausch<br \/>Associate Director, Investor Relations<br \/>+1.781.257.2505 or <a href=\"https:\/\/www.globenewswire.com\/Tracker?data=fXNy6DSaL7FeMUpZ7viXQd3gSs4EHfJs7v8dAiIZj--ngkdw2W1OSkwA6WL0BEhDeLa6SkDEW5xiRY67XghfvrJOHw-Dqk5LoBUj_QPsSIE=\" rel=\"nofollow\" target=\"_blank\" title=\"krausch@tesarobio.com\">krausch@tesarobio.com<\/a><\/p>\n<p class=\"small\" align=\"justify\"><strong>Forward Looking Statements<br \/><\/strong><em>To the extent that statements contained in this press release are not descriptions of historical facts regarding TESARO, they are forward-looking statements reflecting the current beliefs and expectations of management made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Words such as &#8220;may,&#8221; &#8220;will,&#8221; &#8220;expect,&#8221; &#8220;anticipate,&#8221; &#8220;estimate,&#8221; &#8220;intend,&#8221; and similar expressions (as well as other words or expressions referencing future events, conditions, or circumstances) are intended to identify forward-looking statements. Examples of forward-looking statements contained in this press release include, among others, statements regarding the expected timing of the launch of VARUBI IV in the U.S., the expected timing of our planned commercial launch of ZEJULA in Europe, the design and expected timing of initiation and data from our various ongoing and planned niraparib, TSR-042, TSR-033, TSR-022, combination, and other clinical trials, and our expectation to achieve our various key corporate objectives. Forward-looking statements in this release involve substantial risks and uncertainties that could cause our research and pre-clinical development programs, clinical development programs, future results, performance, or achievements to differ significantly from those expressed or implied by the forward-looking statements. Such risks and uncertainties include, among others risks related to competition, the uncertainties inherent in the execution and completion of clinical trials, uncertainties surrounding the timing of availability of data from clinical trials, uncertainties surrounding our ongoing discussions with and potential actions by regulatory authorities, uncertainties regarding regulatory approvals, uncertainties regarding certain expenditures, risks related to manufacturing and supply, risks related to intellectual property, and other matters that could affect the availability or commercial potential of our products and drug candidates. TESARO undertakes no obligation to update or revise any forward-looking statements. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the business of the Company in general, see TESARO&#8217;s Annual Report on Form 10-K for the year ended December 31, 2016, and Quarterly Report on Form 10-Q for the quarter ended June 30, 2017.<\/em><\/p>\n<p class=\"small\" align=\"justify\">\n<table>\n<tr>\n<td colspan=\"17\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\"><strong>TESARO, Inc.<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\"><strong>Unaudited Condensed Consolidated Statements of Operations<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\">(in thousands, except per share amounts)<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"7\"><strong>Three Months Ended<\/strong><br \/><strong> September 30,<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"7\"><strong>Nine Months Ended<\/strong><br \/><strong> September 30,<\/strong><\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td><strong>2016<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td><strong>2017<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td><strong>2016<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td><strong>2017<\/strong><\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">(as revised)(1)<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">(as revised)(1)<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Revenues:<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Product revenue, net:<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>ZEJULA<sup>&reg;&nbsp;<\/sup><\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; &#8211;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 39,375<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; &#8211;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 65,321<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>VARUBI<sup>&reg;<\/sup>\/VARUBY<sup>&reg;<\/sup>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,326<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,380<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,844<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 7,402<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Total product revenue, net<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,326<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 41,755<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,844<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 72,723<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>License, collaboration and other revenues<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 15,661<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 101,011<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 50,253<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 102,580<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Total revenues<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 16,987<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 142,766<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 53,097<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 175,303<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Expenses:<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Cost of sales &#8211; product<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 378<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 6,216<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 691<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 10,280<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Cost of sales &#8211; intangible asset amortization<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 464<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,254<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,391<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 4,723<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Research and development (2)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 60,783<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 73,388<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 163,630<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 210,910<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Selling, general and administrative (2)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 37,685<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 83,998<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 104,052<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 246,239<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Acquired in-process research and development<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,940<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; &#8211;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 9,940<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 7,000<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Total expenses<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 101,250<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 164,856<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 279,704<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 479,152<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Loss from operations<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (84,263<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (22,090<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (226,607<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (303,849<\/td>\n<td>)<\/td>\n<\/tr>\n<tr>\n<td>Interest and other income (expense), net<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (3,587<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (3,048<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (11,377<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (9,941<\/td>\n<td>)<\/td>\n<\/tr>\n<tr>\n<td>Loss before income taxes<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (87,850<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (25,138<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (237,984<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; (313,790<\/td>\n<td>)<\/td>\n<\/tr>\n<tr>\n<td>Provision for income taxes<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; &#8211;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 139<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; &#8211;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 271<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Net loss<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (87,850<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (25,277<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (237,984<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (314,061<\/td>\n<td>)<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Net loss per share applicable to<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>common stockholders &#8211; basic and diluted<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (1.72<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (0.47<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (5.17<\/td>\n<td>)<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; (5.82<\/td>\n<td>)<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Weighted-average number of common<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>shares used in net loss per share applicable<br \/> to common stockholders &#8211; basic and diluted<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 51,151<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 54,241<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 45,994<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 53,971<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\">(1) The Company adopted Financial Accounting Standards Board Accounting Standards Update No. 2014-09 effective January 1, 2017,<\/td>\n<\/tr>\n<tr>\n<td colspan=\"17\">with full retrospective application to January 1, 2015.&nbsp; Results for periods prior to January 1, 2017 have been revised accordingly.<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"9\">(2) Expenses include the following amounts of non-cash stock-based compensation expense:<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"3\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Research and development<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 5,605<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 8,545<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 13,826<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 23,532<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>Selling, general and administrative<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 7,314<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 16,471<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 20,238<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 43,393<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<\/tr>\n<\/table>\n<p class=\"small\"><em>&nbsp;<\/em><\/p>\n<table>\n<tr>\n<td colspan=\"11\"><strong>TESARO, Inc.<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"11\"><strong>Unaudited Condensed Consolidated Balance Sheets<\/strong><\/td>\n<\/tr>\n<tr>\n<td colspan=\"11\">(in thousands)<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\"><strong>December 31,<\/strong><br \/><strong> 2016<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\"><strong>September 30,<\/strong><br \/><strong> 2017<\/strong><\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">(as revised)(1)<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td><strong>Assets<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Current assets:<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">Cash and cash equivalents<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 785,877<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 521,265<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Accounts receivable<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 6,195<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 27,680<\/td>\n<\/tr>\n<tr>\n<td>Inventories<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 14,700<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 50,527<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Other current assets<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 10,515<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 22,257<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Total current assets<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 817,287<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 621,729<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Intangible assets, net<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 12,877<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 43,155<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">Property and equipment, net<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 6,640<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 9,877<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Restricted cash<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 1,694<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,521<\/td>\n<\/tr>\n<tr>\n<td>Other assets<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 3,795<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 8,436<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Total assets<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 842,293<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 685,718<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\"><strong>Liabilities and stockholders&#8217; equity<\/strong><\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Current liabilities:<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Accounts payable<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 5,236<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 5,984<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Accrued expenses<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 68,700<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 123,076<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">Deferred revenue, current<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 95<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 95<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Other current liabilities<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,978<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 2,287<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Total current liabilities<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 77,009<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 131,442<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Convertible notes, net<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 131,775<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 140,362<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">Deferred revenue, non-current<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 305<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 235<\/td>\n<\/tr>\n<tr>\n<td colspan=\"3\">Other non-current liabilities<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 5,086<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 6,318<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Total liabilities<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 214,175<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 278,357<\/td>\n<\/tr>\n<tr>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">Total stockholders&#8217; equity<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 628,118<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp; 407,361<\/td>\n<\/tr>\n<tr>\n<td colspan=\"4\">Total liabilities and stockholders&#8217; equity<\/td>\n<td>&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 842,293<\/td>\n<td>&nbsp;<\/td>\n<td>$<\/td>\n<td>&nbsp; 685,718<\/td>\n<\/tr>\n<tr>\n<td colspan=\"5\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"11\">(1) The Company adopted Financial Accounting Standards Board Accounting Standards<\/td>\n<\/tr>\n<tr>\n<td colspan=\"11\">Update No. 2014-09 effective January 1, 2017, with full retrospective application to January 1,<\/td>\n<\/tr>\n<tr>\n<td colspan=\"9\">2015.&nbsp; Results for periods prior to January 1, 2017 have been revised accordingly.<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<tr>\n<td colspan=\"5\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<td>&nbsp;<\/td>\n<td colspan=\"2\">&nbsp;<\/td>\n<\/tr>\n<\/table>\n<p class=\"small\"><\/p><\/p>\n","protected":false},"author":74553,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[71350,71360],"tags":[],"_links":{"self":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts\/554832"}],"collection":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/users\/74553"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/comments?post=554832"}],"version-history":[{"count":0,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts\/554832\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/media?parent=554832"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/categories?post=554832"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/tags?post=554832"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}