{"id":11963,"date":"2015-04-07T17:31:55","date_gmt":"2015-04-07T17:31:55","guid":{"rendered":"https:\/\/www.pm360online.com\/antihistamine-drug-chlorcyclizine-shows-promise-for-treating-hcv\/"},"modified":"2015-04-07T17:31:55","modified_gmt":"2015-04-07T17:31:55","slug":"antihistamine-drug-chlorcyclizine-shows-promise-for-treating-hcv","status":"publish","type":"post","link":"https:\/\/www.pm360online.com\/antihistamine-drug-chlorcyclizine-shows-promise-for-treating-hcv\/","title":{"rendered":"Antihistamine drug chlorcyclizine shows promise for treating HCV"},"content":{"rendered":"<p>Repurposing the antihistamine medication chlorcyclizine may be a viable option in the treatment of hepatitis C, reported Dr. Shanshan He and coauthors.<\/p>\n<p>In a study of mice carrying human hepatocytes infected with hepatitis C virus, chlorcyclizine significantly inhibited infection of HCV genotypes 1b and 2a without drug resistance at 4 and 6 weeks of treatment (<em>P<\/em> &lt; .05), respectively, Dr. He and associates reported.<\/p>\n<p>The findings suggest that the use of chlorcyclizine in treating HCV infection may \u201cprovide a more affordable alternative to the current costly options, especially in low-resource settings where chronic HCV infection is endemic,\u201d the investigators said in the paper.<\/p>\n<p>Read the full article in Science Translational Medicine 2015 at: <span>                                    <a href=\"http:\/\/stm.sciencemag.org\/lookup\/doi\/10.1126\/scitranslmed.3010286\">doi\/10.1126\/scitranslmed.3010286<\/a>.<\/span>                            <\/p>\n<p>                                <span>                                    <a href=\"mailto:ginews%40gastro.org%20%20?subject=\">ginews@gastro.org<\/a>                                <\/span>                            <\/p>\n","protected":false},"excerpt":{"rendered":"<p class=\"small\">Repurposing the antihistamine medication chlorcyclizine may be a viable option in the treatment of hepatitis C, reported Dr. Shanshan He &#8230;<\/p>\n","protected":false},"author":59236,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[56416,56424,56425],"tags":[],"_links":{"self":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts\/11963"}],"collection":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/users\/59236"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/comments?post=11963"}],"version-history":[{"count":0,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/posts\/11963\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/media?parent=11963"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/categories?post=11963"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pm360online.com\/wp-json\/wp\/v2\/tags?post=11963"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}