Collaboration Expands Platform’s Reach Beyond Cancer and Autoimmune Disease to Address T cell Exhaustion in Chronic Infectious Diseases
CAMBRIDGE, Mass., Oct. 17, 2018 (GLOBE NEWSWIRE) -- Cue Biopharma, Inc., (NASDAQ: CUE) an innovative immunotherapy company developing a novel, proprietary class of biologics engineered to selectively modulate the human immune system to treat cancer, autoimmune and chronic infectious diseases, announced today that the company has entered into a strategic research collaboration with Albert Einstein College of Medicine to advance the next generation of Immuno-STAT™ biologics for chronic infectious diseases.
“We are very pleased to expand our relationship with Albert Einstein College of Medicine, and believe this collaboration will enhance our capabilities and capacity to study and develop Immuno-STAT™ biologics to address T cell exhaustion,” said Daniel Passeri, M.Sc., J.D., President and Chief Executive Officer of Cue Biopharma. “This strategic collaboration should provide us with enhanced capacity for bringing our selective T cell modulation Immuno-STAT™ platform to the clinic for more diverse applications, such as chronic infectious diseases.”
“We look forward to furthering our relationship with Einstein and to working with world class researchers to expand the therapeutic reach of our Immuno-STAT™ platform,” said Anish Suri, Ph.D., and Chief Scientific Officer of Cue Biopharma. "Through our collaboration we aim to leverage the modularity and selectivity of the platform to expand the therapeutic reach of our biologics beyond cancer and autoimmune disease to chronic infectious disease where overcoming T cell exhaustion has been a challenge.”
“Cue Biopharma's platform for selective modulation of T cells holds great promise and I believe through this collaboration we will be able to continue to advance the next generation of Immuno-STAT™ biologics,” said Steven C. Almo, Ph.D., Professor and Chair of Biochemistry, Professor of Physiology & Biophysics and the Wollowick Family Foundation Chair in Multiple Sclerosis and Immunology at Einstein, and co-founder of Cue Biopharma. “Chronic infectious disease is a natural area for expansion and I look forward to working with the company to further explore this opportunity to develop innovative therapeutic strategies that address unmet medical needs."
Collaborating with Dr. Almo is Harris Goldstein, M.D., Director of the Center for AIDS Research at Einstein, where he is also Professor of Microbiology & Immunology, Professor of Pediatrics and the Charles Michael Chair in Autoimmune Diseases.
About Cue Biopharma
Cue Biopharma is an innovative immunotherapy company developing a novel, proprietary class of biologics engineered to selectively modulate the human immune system to treat a broad range of cancers, autoimmune and chronic infectious diseases. We design biologics to engage and modulate the activity of disease-associated T cells in the patient’s body, with the goal of offering significant therapeutic benefits while potentially minimizing or eliminating unwanted side effects.
We believe our selective biologics allow us to target antigen-specific T cell populations in a variety of indications using a peptide – MHC complex for delivering T cell modulating effectors, such as IL-2. Once a biologic has been optimized, our approach offers the potential for readily exchanging peptides to target different T cell populations and indications using previously-validated drug frameworks developed from the Immuno-STAT™ (Selective Targeting and Alteration of T cells) platform. This flexibility could truncate the drug selection and development process, moving effective therapeutics from discovery to clinical validation more rapidly and cost-efficiently than current industry standard timelines and costs.
Headquartered in Cambridge, MA, we are led by an experienced management team and scientific and clinical advisory board (SAB/CAB) with deep expertise in the design and clinical development of protein biologics, immunology and immuno-oncology.
For more information, visit www.cuebio.com.
This press release contains “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that are intended to be covered by the “safe harbor” created by those sections. Forward-looking statements, which are based on certain assumptions and describe our future plans, strategies and expectations, can generally be identified by the use of forward-looking terms such as “believe,” “expect,” “may,” “will,” “should,” “would,” “could,” “seek,” “intend,” “plan,” “goal,” “project,” “estimate,” “anticipate,” “strategy,” “future,” “likely” or other comparable terms. All statements other than statements of historical facts included in this press release regarding our strategies, prospects, financial condition, operations, costs, plans and objectives are forward-looking statements. Examples of forward-looking statements include, among others, statements we make regarding anticipated results of our drug development efforts, including study results, our expectations regarding regulatory developments and expected future operating results. Forward-looking statements are neither historical facts nor assurances of future performance. Instead, they are based only on our current beliefs, expectations and assumptions regarding the future of our business, future plans and strategies, projections, anticipated events and trends, the economy and other future conditions. Because forward-looking statements relate to the future, they are subject to inherent uncertainties, risks and changes in circumstances that are difficult to predict and many of which are outside of our control. Our actual results and financial condition may differ materially from those indicated in the forward-looking statements. Therefore, you should not rely on any of these forward-looking statements. Important factors that could cause our actual results and financial condition to differ materially from those indicated in the forward-looking statements include, among others, our limited operating history, limited cash and a history of losses; our ability to achieve profitability; our ability to secure required U.S. Food and Drug Administration (“FDA”) or other governmental approvals for our product candidates and the breadth of any approved indication; negative or inconclusive results from our clinical studies or serious and unexpected drug-related side effects or other safety issues experienced by participants in our clinical trials; delays and changes in regulatory requirements, policy and guidelines including potential delays in submitting required regulatory applications to the FDA; our reliance on licensors, collaborations and strategic alliances; our ability to obtain adequate financing to fund our business operations in the future; and the other risks and uncertainties described in the Risk Factors and in Management's Discussion and Analysis of Financial Condition and Results of Operations sections of our most recently filed Annual Report on Form 10-K and any subsequently filed Quarterly Report(s) on Form 10-Q. Any forward-looking statement made by us in this press release is based only on information currently available to us and speaks only as of the date on which it is made. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time to time, whether as a result of new information, future developments or otherwise.
Sam Brown Inc