Top News Stories

  • Anticoagulant resumption after ICH aids patients

    on February 24th, 2017
    AT THE INTERNATIONAL STROKE CONFERENCE HOUSTON (FRONTLINE MEDICAL NEWS) – Even when patients on an oral anticoagulant have the dreaded complication of an intracerebral hemorrhage, resumption of their oral anticoagulation regimen appears to produce the best midterm outcomes, based on a meta-analysi[...]
  • Exercise can boost cognition after stroke

    on February 23rd, 2017
    AT THE INTERNATIONAL STROKE CONFERENCE HOUSTON (FRONTLINE MEDICAL NEWS) – Exercise seems to improve some of the cognitive difficulties that can manifest in stroke survivors, even if patients don’t hit the gym for a couple of years after the incident. A meta-analysis of 14 randomized, controlled [...]
  • Lanadelumab reduced hereditary angioedema attacks by 88%-100%

    on February 22nd, 2017
    FROM THE NEW ENGLAND JOURNAL OF MEDICINE Lanadelumab, a monoclonal antibody that inhibits kallikrein, reduced attacks of hereditary angioedema with C1 inhibitor deficiency by 88%-100% in a small, phase I trial. Hereditary angioedema with C1 inhibitor deficiency is a rare disorder characterized by un[...]
  • Testosterone Trials’ cardiac, cognitive results disappoint

    on February 22nd, 2017
    FROM JAMA AND JAMA INTERNAL MEDICINE Testosterone treatment may have beneficial effects on unexplained anemia or bone density in men with age-related low testosterone, but at the cost of an increase in coronary artery plaque and with no benefit on cognitive function, new research suggests. The resul[...]
  • Hormone therapy prolongs PFS in rare low-grade serous cancer

    on February 21st, 2017
    FROM THE JOURNAL OF CLINICAL ONCOLOGY Hormone maintenance therapy, when given after primary cytoreductive surgery and platinum-based chemotherapy, prolonged progression-free survival among women who had low-grade serous carcinoma of the ovary or peritoneum, a study showed. Low-grade serous carcinoma[...]
  • Collaborative care aids seniors’ mild depression

    on February 21st, 2017
    FROM JAMA A collaborative care model significantly mitigated mild depression in adults aged 65 and older, compared with usual care in the short term, based on data from 705 patients. The findings were published online Feb. 21. “There is limited research about older people with mild depressive diso[...]
  • No AR in CTCs linked with better survival in advanced prostate cancer

    on February 17th, 2017
    FROM THE GENITOURINARY CANCERS SYMPOSIUM The presence and amount of full-length androgen receptor biomarker detected in the circulating tumor cells of people with metastatic castration-resistant prostate cancer can inform prognosis, a prospective study reveals. Investigators report significant diffe[...]
  • Survival gains with pembrolizumab in urothelial cancer

    on February 17th, 2017
    FROM THE GENITOURINARY CANCERS SYMPOSIUM Treatment with checkpoint inhibitor pembrolizumab is associated with significant gains in overall survival among patients with treatment-refractory advanced urothelial carcinoma, according to new research. Data from the KEYNOTE-045 trial was presented simulta[...]
  • RNA-based biopsy test bests NCCN risk stratification for PC prognosis

    on February 17th, 2017
    AT THE GENITOURINARY CANCERS SYMPOSIUM ORLANDO (FRONTLINE MEDICAL NEWS) – A genetic assay for prostate cancer typically used after radical prostatectomy could be used earlier, at the time of diagnostic biopsy testing, to classify patients as low, intermediate, and high risk for metastasis and dise[...]
  • Prostate cancer susceptibility loci identified

    on February 17th, 2017
    AT THE GENITOURINARY CANCERS SYMPOSIUM ORLANDO (FRONTLINE MEDICAL NEWS) – A large analysis has identified 65 novel prostate cancer susceptibility loci, including an early-onset locus, and captured an additional 6% of the familial relevant risk for prostate cancer. In the Oncoarray stratified analy[...]
  • Seema Verma dodges questions on how to improve CMS

    on February 16th, 2017
    FROM A SENATE FINANCE COMMITTEE HEARING If confirmed as Centers for Medicare & Medicaid Services administrator, Seema Verma vowed to modernize CMS programs, improve Medicaid access, and leverage technology to drive better care, but she stopped short of explaining how she would do so during her c[...]
  • Brodalumab approved for psoriasis with REMS required

    on February 16th, 2017
    The Food and Drug Administration has approved brodalumab, an interleukin-17 receptor A-antagonist, for treating adults with moderate to severe plaque psoriasis, with a Risk Evaluation and Mitigation Strategy (REMS) that addresses the “observed risk of suicidal ideation and behavior” in clinical [...]
  • More periviable infants survive without neurodevelopmental impairment

    on February 16th, 2017
    FROM THE NEW ENGLAND JOURNAL OF MEDICINE Among periviable infants born at 11 tertiary care centers in 2000 through 2011, the rate of survival without neurodevelopmental impairment increased a small but significant 4%, according to a report published online Feb. 16 in the New England Journal of Medic[...]
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