• SPECT reveals perfusion problems in antiphospholipid syndrome

    on March 27th, 2017
    AT LUPUS 2017 MELBOURNE (FRONTLINE MEDICAL NEWS) – SPECT imaging can identify abnormalities in brain perfusion in patients with multiple antiphospholipid antibodies and neuropsychiatric symptoms, but without a history of thrombosis, according to a study presented at an international congress on sy[...]
  • Etanercept found not optimal for reducing anterior uveitis in ankylosing spondylitis

    on March 21st, 2017
    FROM ANNALS OF THE RHEUMATIC DISEASES Two anti–tumor necrosis factor monoclonal antibodies, adalimumab and infliximab, showed evidence of being markedly more effective than the anti-TNF–receptor inhibitor etanercept at reducing the rate of anterior uveitis in patients with ankylosing spondylitis[...]
  • Osteoarthritis’ link to metabolic syndrome tied to body weight, BMI

    on March 21st, 2017
    FROM ARTHRITIS & RHEUMATOLOGY The metabolic syndrome’s association with the development of osteoarthritis appears to occur primarily through the influence of factors related to body weight or body mass index, according to an analysis of data from the longitudinal Framingham osteoarthritis stud[...]
  • Anti-TNF agents show clinical benefit in refractory sarcoidosis

    on March 20th, 2017
    FROM SEMINARS IN ARTHRITIS & RHEUMATISM Around two-thirds of patients with severe or refractory sarcoidosis show a significant clinical response to tumor necrosis factor (TNF) antagonists, according to findings from a retrospective, multicenter cohort study. Biologic agents targeting TNF, such a[...]
  • Clinicians still seek the best uses for apremilast

    on March 20th, 2017
    EXPERT ANALYSIS FROM SDEF HAWAII DERMATOLOGY SEMINAR WAILEA, HAWAII (FRONTLINE MEDICAL NEWS) – Oral apremilast is a drug in search of a compelling indication, Craig L. Leonardi, MD, declared at the Hawaii Dermatology Seminar provided by Global Academy for Medical Education/Skin Disease Research Fo[...]
  • Seven shortcuts help with diagnosis of CNS vasculitis

    on March 14th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – A lumbar puncture is indispensable when entertaining the diagnosis of primary angiitis of the CNS, Leonard H. Calabrese, DO, declared at the Winter Rheumatology Symposium sponsored by the American Col[...]
  • No benefit found for routine inpatient rehab after knee replacement

    on March 14th, 2017
    FROM JAMA A new randomized study from Australia suggests that for many patients, brief inpatient rehabilitation after knee replacement provides no benefits in several measures, compared with rehab at home. However, “we are not concluding that there is no role for inpatient rehabilitation after kne[...]
  • U.S. chikungunya epidemic would likely put rheumatologists on front line

    on March 13th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – The continental United States is vulnerable to an epidemic of chikungunya virus disease, an event which would have profound consequences for rheumatologists, Robert T. Schoen, MD, said at the Winter R[...]
  • No rise in CV events seen with tocilizumab

    on March 10th, 2017
    FROM ARTHRITIS & RHEUMATOLOGY Patients with refractory rheumatoid arthritis who switched to tocilizumab showed no increased cardiovascular risk when compared with those who switched to a tumor necrosis factor inhibitor in a large cohort study. Rheumatoid arthritis is known to approximately doubl[...]
  • Biomarker score not predictive of successful TNF inhibitor tapering in RA

    on March 10th, 2017
    FROM RHEUMATOLOGY A multi-biomarker disease activity score in patients with longstanding rheumatoid arthritis and low disease activity prior to tapering adalimumab or etanercept did not predict flare-related outcomes in an 18-month, open-label, randomized clinical trial. These findings seemed “rob[...]
  • Methotrexate use justified for early RA, disease prevention

    on March 9th, 2017
    FROM ARTHRITIS & RHEUMATOLOGY Efforts to delay or prevent rheumatoid arthritis (RA) in individuals at high risk for the disease received a boost from the findings of a subgroup analysis of an older Dutch prevention trial involving methotrexate that were published recently in Arthritis & Rheu[...]
  • Dactylitis signals more severe psoriatic arthritis

    on March 8th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – Dactylitis is a common and painful extra-articular manifestation of psoriatic arthritis that takes on added clinical significance because it’s also a marker of greater disease severity, Christopher [...]
  • Expert provides deeper insight into tocilizumab for giant cell arteritis

    on March 8th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – The sustained remission rate in patients with giant cell arteritis was three times better with subcutaneous tocilizumab than with long-term prednisone in the landmark GiACTA trial, John H. Stone, MD, [...]
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