Oncology

  • PREMM5: Updated Lynch syndrome test available

    on May 22nd, 2017
    FROM THE JOURNAL OF CLINICAL ONCOLOGY An updated Lynch syndrome (LS) prediction model improves accuracy and may be used to assess individuals who are currently unaffected by cancer. The model predicts an individual’s risk of carrying one of five known gene mutations associated with LS. It could be[...]
  • Skin cancer risk similar for liver and kidney transplant recipients

    on May 22nd, 2017
    AT ACDASM 2017 SYDNEY (FRONTLINE MEDICAL NEWS) – The risk of developing nonmelanoma skin cancer among liver transplant recipients is similar to that among kidney transplant recipients, but the former tend to have more skin cancer risk factors at baseline, according to a longitudinal cohort study r[...]
  • Healthy lifestyle, tree nuts may protect against colon cancer recurrence

    on May 22nd, 2017
    FROM THE 2017 ASCO ANNUAL MEETING Oncologists whose patients with treated early colon cancer ask what they can do to prevent it from coming back can now more strongly endorse lifestyle modification, based on findings from a pair of cohort studies reported at a presscast leading up to the annual meet[...]
  • In good-candidate CLL, don’t wait too long for alloHCT

    on May 22nd, 2017
    AT THE IWCLL MEETING NEW YORK (FRONTLINE MEDICAL NEWS) – Allogeneic hematopoietic stem cell transplantation (alloHCT) using HLA-compatible donors results in excellent long-term progression-free survival in younger high-risk chronic lymphocytic leukemia (CLL) patients, an analysis of data from a Eu[...]
  • Forgo axillary dissection for single suspicious node on ultrasound

    on May 22nd, 2017
    AT ASBS 2017 LAS VEGAS (FRONTLINE MEDICAL NEWS) – About half of breast cancer patients without palpable lymphadenopathy but with preoperative ultrasound-guided, biopsy-proven axillary lymph node metastases have N1 disease, according to a review of 129 women. Among the 30 women with a primary tumor[...]
  • Intraoperative radiation looks good for DCIS

    on May 22nd, 2017
    At ASBS 2017 LAS VEGAS (FRONTLINE MEDICAL NEWS) – Intraoperative radiation therapy (IORT) is effective in patients with ductal carcinoma in situ (DCIS), and bilateral digital mammography and breast MRI effectively predicted which patients would be most suited for the procedure, according to a nonr[...]
  • Early allo SCT advised for high-risk mantle cell lymphoma

    on May 22nd, 2017
    FROM ASCO 2017 ANNUAL MEETING High-risk patients with mantle cell lymphoma who have a matched related donor have a better chance for survival if they don’t delay allogeneic hematopoietic stem cell transplantation (allo SCT), based on a small single-center study reported by Daniel Allen Kobrinski, [...]
  • Ibrutinib response in CLL/SLL less affected by select risk factors

    on May 22nd, 2017
    AT THE IWCLL MEETING NEW YORK (FRONTLINE MEDICAL NEWS) – Risk factors associated with poor outcomes in chronic lymphocytic leukemia/small lymphocytic leukemia patients treated with standard therapies appear to have less relevance with ibrutinib treatment, according to an integrated analysis of dat[...]
  • Positive node risk defined for elderly breast cancer patients

    on May 22nd, 2017
    AT ASBS 2017 LAS VEGAS (FRONTLINE MEDICAL NEWS) – In women aged 70 years or older with hormone receptor–positive invasive breast cancer, their tumor size, grade, and histology – but not human epidermal growth factor receptor–2 status – predicted nodal positivity, according to a retrospecti[...]
  • ALC/AMC prognostic in mantle cell lymphoma

    on May 19th, 2017
    IN CONJUNCTION WITH ASCO 2017 The peripheral blood absolute lymphocyte-to-monocyte ratio (ALC/AMC) was prognostic for overall survival in mantle cell lymphoma patients who have undergone induction therapy, based on a retrospective review study of 96 patients by Andre Goy, MD, of John Theurer Cancer [...]
  • Smoldering myeloma progressed more rapidly in patients with elevated BMIs

    on May 19th, 2017
    FROM ASCO 2017 An elevated body mass index appears to be a risk factor for progression of smoldering multiple myeloma, according to Wilson I. Gonsalves, MD, and his colleagues at Mayo Clinic, Rochester, Minn. The findings, based on median follow up data of 106 months from 306 patients diagnosed with[...]
  • Omitting ALND in some breast cancer patients may be the right choice

    on May 19th, 2017
    AT THE ANNUAL ASA MEETING PHILADELPHIA (FRONTLINE MEDICAL NEWS) – The safety of sentinel lymph node biopsy (SLNB) alone without axillary lymph node dissection (ALND) had been established for patients with cT1-2N0 cancer with one or two positive sentinel lymph nodes who undergo breast conservation [...]
  • Myeloma patients who get solid tumor cancers do as well as other cancer patients

    on May 19th, 2017
    FROM 2017 ASCO ANNUAL MEETING With improved treatment, patients with multiple myeloma are surviving long enough to develop other cancers, Jorge J. Castillo, MD, and Adam J. Olszewski, MD, reported in a poster to be presented at the annual meeting of the American Society of Clinical Oncology. The goo[...]
Back to top