Neurology

  • Screen opioid users for depression, study recommends

    on January 13th, 2017
    FROM THE JOURNAL OF AFFECTIVE DISORDERS Depression combined with chronic opioid analgesic use involves more symptoms and comorbidities than depression without chronic opioid use, according to a study of Department of Veterans Affairs patients seen between 2000 and 2012. “Screening and treatment of[...]
  • Older adults can sustain asymptomatic cervical fractures

    on January 11th, 2017
    HOLLYWOOD, FLA. (FRONTLINE MEDICAL NEWS) – Silent cervical fractures may be common among older trauma patients, a retrospective study has determined. The 4-year review found that 21% of older patients with a confirmed C-spine fracture reported no pain on history or physical exam, and that 76% of t[...]
  • Children with infantile spasms or nonsyndromic epilepsy achieve similar outcomes

    on January 11th, 2017
    AT AES 2016 Houston (FRONTLINE MEDICAL NEWS) – Infants and children who had epilepsy that was not identified as being part of a syndrome fared slightly worse in developmental outcomes and pharmacoresistance than did those with West syndrome/infantile spasms, Dravet syndrome, or another type of syn[...]
  • Chest-worn seizure detection device shows promise

    on January 10th, 2017
    AT AES 2016 HOUSTON (FRONTLINE MEDICAL NEWS) – An investigative, chest-worn device shows promise for detecting a wide range of seizure types in children with epilepsy, results from a small single-center study showed. “Our goal is for parents to have more peace of mind, not feeling like they have[...]
  • Giant cell arteritis independently raises risk for venous thromboembolism

    on January 10th, 2017
    FROM ARTHRITIS & RHEUMATOLOGY The risk of venous thromboembolism increases markedly shortly before the diagnosis of giant cell arteritis regardless of glucocorticoid exposure, peaks at the time of diagnosis, and then progressively declines, according to a matched cohort review involving more tha[...]
  • Study highlights need to address vitamin D deficiency in epilepsy patients

    on January 9th, 2017
    AT AES 2016 HOUSTON (FRONTLINE MEDICAL NEWS) – Neurologists and other clinicians ordered vitamin D levels, dual-energy x-ray absorptiometry (DXA) scans, and vitamin D supplementation for epilepsy patients in order to diagnose and prevent vitamin D deficiency and osteopenia, results from a single-c[...]
  • First drug for spinal muscular atrophy approved

    on January 6th, 2017
    The antisense oligonucleotide drug nusinersen is the first therapy approved by the U.S. Food and Drug Administration to treat children and adults with spinal muscular atrophy. The drug was developed by Ionis Pharmaceuticals and will be marketed by Biogen under the brand name Spinraza. The antisense [...]
  • Depression further boosts stroke risk in A-fib

    on January 5th, 2017
    AT THE AHA SCIENTIFIC SESSIONS NEW ORLEANS (FRONTLINE MEDICAL NEWS) – Depression increases the risk of stroke in patients with atrial fibrillation, Bruno B. Lima, MD, reported at the American Heart Association scientific sessions. This novel finding from what’s believed to be the first prospecti[...]
  • Project aims to improve understanding of AED prescribing trends

    on January 5th, 2017
    AT AES 2016 HOUSTON (FRONTLINE MEDICAL NEWS) – A significant proportion of epilepsy patients in the United States are not taking newer antiepileptic medications, results from a pilot study suggested. The finding comes from the Connectors Project, a collaboration between the Epilepsy Foundation and[...]
  • Staying open versus closed at the end of the year

    on January 5th, 2017
    To the horror of many colleagues, I close my office for the last 2 weeks of each year. I went back to work on Jan. 3. For several years, I didn’t close for that long. My staff and I would try to work out who needed what days off for family holiday stuff, and try […][...]
  • Myth of the Month: CT scan before lumbar puncture in suspected meningitis?

    on January 4th, 2017
    A 28-year-old male presents to the emergency department with fever and severe headache. He has had a fever for 24 hours. Headache began that morning. On exam, he has marked nuchal rigidity, with a temperature of 103.5° F. He is fully oriented and has a nonfocal neurologic examination. What would yo[...]
  • Infantile spasms diagnosis, treatment too often delayed

    on January 4th, 2017
    AT AES 2016 HOUSTON (FRONTLINE MEDICAL NEWS) – The appropriate evaluation and treatment of infantile spasms often comes after significant delays that are largely attributable to lack of recognition of the condition, according to recent survey results. “Parental suspicions that ‘something was w[...]
  • Hypothermia does not provide neuroprotection during convulsive status epilepticus

    on January 4th, 2017
    FROM NEW ENGLAND JOURNAL OF MEDICINE Adding hypothermia therapy to standard care for convulsive status epilepticus is not neuroprotective, according to a report published online Dec. 22 in the New England Journal of Medicine. Small-animal studies recently reported that therapeutic hypothermia had an[...]
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