Nephrology and Urology

  • Ultrasound, cystoscopy combo tops CT for asymptomatic microscopic hematuria

    on April 17th, 2017
    FROM JAMA INTERNAL MEDICINE Combining renal ultrasound and bladder cystoscopy is the most cost-effective approach for the initial evaluation of asymptomatic microscopic hematuria, even among patients at risk for genitourinary malignancy, according to a report published online April 17 in JAMA Intern[...]
  • MicroRNAs linked to treatment response in lupus nephritis

    on April 10th, 2017
    AT LUPUS 2017 MELBOURNE (FRONTLINE MEDICAL NEWS) – Researchers have identified six microRNAs that may indicate a better likelihood of response to cyclophosphamide in patients with lupus nephritis, according to a study presented at an international conference on systemic lupus erythematosus. “Mic[...]
  • Metformin linked with better survival in RCC patients with diabetes

    on April 10th, 2017
    Metformin use was associated with better survival for patients with renal cell carcinoma and diabetes in a meta-analysis, investigators report. Yang Li, MD, and associates at Chongqing (China) Medical University, performed a pooled analysis of data from 254,329 patients with both localized and metas[...]
  • Alpha-blockers deemed safe in heart failure

    on April 5th, 2017
    At ACC 17 WASHINGTON (FRONTLINE MEDICAL NEWS) – Prescribing alpha-adrenergic blocking agents for treatment of benign prostatic hypertrophy in men with heart failure proved to be not only safe, but also was associated with significantly reduced rates of both heart failure readmission and all-cause [...]
  • Lupus nephritis expert offers management tips

    on April 4th, 2017
    EXPERT ANALYSIS FROM LUPUS 2017 MELBOURNE (FRONTLINE MEDICAL NEWS) – Multidisciplinary management of comorbidities is one of the most important aspects of the care of patients with lupus nephritis, Frédéric Houssiau, MD, PhD, said at an international congress on systemic lupus erythematosus. In [...]
  • Vascular involvement may signify worse outcomes in lupus nephritis

    on March 29th, 2017
    AT LUPUS 2017 MELBOURNE (FRONTLINE MEDICAL NEWS) – Vascular involvement in patients with lupus nephritis is associated with poorer outcomes and could be a trigger for a more aggressive treatment approach, according to observational study results reported at an international congress on systemic lu[...]
  • Biomarker combination may forecast remission in lupus nephritis

    on March 29th, 2017
    AT LUPUS 2017 MELBOURNE (FRONTLINE MEDICAL NEWS) – A reduction in urinary protein creatinine ratio and normalization of inflammatory biomarkers early in treatment of lupus nephritis may predict response rates at 24 and 48 weeks, according to data from the AURION study presented at an international[...]
  • AKI seen in 64% of children hospitalized with diabetic ketoacidosis

    on March 13th, 2017
    FROM JAMA PEDIATRICS A high proportion of children with type 1 diabetes who are hospitalized for diabetic ketoacidosis (DKA) develop acute kidney injury (AKI), according to results from a study. Researchers reviewing records from a Canadian hospital found that in a cohort of 165 children hospitalize[...]
  • No benefit from adjuvant sunitinib or sorafenib for clear cell renal cancer

    on March 9th, 2017
    FROM JAMA ONCOLOGY Adjuvant sunitinib or sorafenib show no significant advantages in disease-free or overall survival over placebo in patients with high-risk clear cell renal cancer, according to secondary analysis of data from the ASSURE trial. The primary analysis of data from the ASSURE trial, wh[...]
  • Voclosporin linked to threefold increase in lupus nephritis remission

    on March 6th, 2017
    Treatment with the investigational calcineurin inhibitor voclosporin is associated with a significant, threefold-higher rate of complete remission for lupus nephritis, compared with the current standard of care, according to 48-week data from the AURA-LV (Aurinia Urinary Protein Reduction Active–L[...]
  • Chemo gives no boost to ADT for patients with localized prostate cancer

    on March 1st, 2017
    FROM THE GENITOURINARY CANCERS SYMPOSIUM Mitoxantrone plus prednisone (MP) added to androgen deprivation therapy (ADT) does not improve outcomes in patients with clinically localized prostate cancer, according to the results of a large long-term multicenter clinical trial. At a follow-up time of alm[...]
  • ‘Strong evidence’ links obesity to cancers

    on March 1st, 2017
    FROM BMJ There is strong evidence linking adiposity to esophageal adenocarcinoma, multiple myeloma, and cancer of the colon, rectum, biliary tract, pancreas, endometrium, kidney, and postmenopausal breast, according to the authors of an umbrella review published in the Feb. 28 edition of the BMJ. [...]
  • Genomic differences seen in mRCC during first- and second-line therapy

    on February 28th, 2017
    AT THE GENITOURINARY CANCERS SYMPOSIUM ORLANDO (FRONTLINE MEDICAL NEWS) – In the largest assessment to date of circulating tumor DNA (ctDNA) in patients with metastatic renal cell carcinoma (mRCC), the majority of patients were found to have clinically relevant genomic alterations. The most freque[...]
Back to top