Infectious diseases

  • Two-drug combo looks good for HIV maintenance therapy

    on February 22nd, 2017
    AT CROI SEATTLE (FRONTLINE MEDICAL NEWS) – In HIV patients with suppressed virus and no history of virologic failure, a two-drug combination of dolutegravir and rilpivirine (DTG+RPV) proved noninferior to three- and four-drug regimens in maintaining viral RNA counts at less than 50 copies/mL. The [...]
  • Factors may flag kids at high risk for C. difficile recurrence

    on February 22nd, 2017
    FROM THE PEDIATRIC INFECTIOUS DISEASE JOURNAL The identification of risk factors associated with recurrent Clostridium difficile infection (rCDI) might allow early recognition of those children at highest risk, said Dr. Maribeth Nicholson of Vanderbilt University, Nashville, Tenn., and her associate[...]
  • Prednisone reduces TB-IRIS risk

    on February 22nd, 2017
    AT CROI SEATTLE (FRONTLINE MEDICAL NEWS) – In patients coinfected with HIV and tuberculosis, addition of prednisone to an antiretroviral therapy (ART)/TB regimen significantly reduced the incidence of tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS). The study showed a reduction [...]
  • Mycobacterium tuberculosis: Overcoming one obstacle on the road to elimination

    on February 22nd, 2017
    March 24 is World TB Day. It was on this date in 1882 that physician Robert Koch announced the discovery of Mycobacterium tuberculosis, the causative agent of tuberculosis. Worldwide, activities are planned to raise awareness of TB and to support initiatives for prevention, better control, and ultim[...]
  • Infections boost postop wound dehiscence risk

    on February 22nd, 2017
    AT THE ACADEMIC SURGICAL CONGRESS SAN DIEGO (FRONTLINE MEDICAL NEWS) – Pre- and postsurgical infections top the list of factors in putting patients at risk of wound dehiscence after laparotomy, a database study has found. Before surgery, a contaminated or dirty wound and sepsis doubled the risk of[...]
  • LEEP tops cryotherapy for cervical dysplasia in women with HIV

    on February 21st, 2017
    AT CROI SEATTLE (FRONTLINE MEDICAL NEWS) – HIV-positive women treated with cryotherapy for cervical intraepithelial neoplasia (CIN) 2/3 were 52% more likely than women treated with loop excision to have a recurrence within 2 years, according to a randomized trial in Kenya. The investigators called[...]
  • Pertussis susceptibility estimates call for public health push

    on February 21st, 2017
    FROM THE PEDIATRIC INFECTIOUS DISEASE JOURNAL Estimates of high pertussis susceptibility in infants suggest a need for greater public health efforts to increase DTaP vaccine coverage in children and Tdap coverage in pregnant women, according to results of research by Lana Childs and Robert A. Bednar[...]
  • Zika slowing, but not going away

    on February 17th, 2017
    New cases of pregnant women with laboratory evidence of Zika virus infection were down for the 2 weeks ending Feb. 7, with a big drop in the U.S. territories offsetting an increase among the 50 states and the District of Columbia, according to the Centers for Disease Control and Prevention. There we[...]
  • Zika slowing, but not going away

    on February 17th, 2017
    New cases of pregnant women with laboratory evidence of Zika virus infection were down for the 2 weeks ending Feb. 7, with a big drop in the U.S. territories offsetting an increase among the 50 states and the District of Columbia, according to the Centers for Disease Control and Prevention. There we[...]
  • Vitamin D reduces respiratory infection risk

    on February 17th, 2017
    FROM THE BMJ Administering doses of a vitamin D supplement to patients can significantly mitigate their risk of developing acute respiratory tract infections, according to a recent study published by the BMJ. “[Existing] epidemiological and in vitro data have prompted numerous randomized controlle[...]
  • Hepatitis Outlook: January 2017

    on February 15th, 2017
    If you work on the front lines of medical care treating patients with hepatitis, you may not have time to review all the hepatitis research that enters the medical literature every month. Here’s a quick look at some notable news items and journal articles published over the past month, covering th[...]
  • Daptomycin safe, effective for pediatric cSSSI treatment

    on February 15th, 2017
    FROM PEDIATRICS Daptomycin was safe and effective at treating complicated skin and skin structure infections (cSSSI) in children aged 1-17 years, according to Dr. John Bradley of the University of California, San Diego, and his associates. A total of 389 cSSSI patients were included in the study, wi[...]
  • Cost equilibrium in Canada: Inpatient and outpatient treatment of herpes zoster

    on February 14th, 2017
    FROM BMC INFECTIOUS DISEASES Rates of herpes zoster infections have increased substantially since the late 1990s in Canada. This, combined with rising per-episode medical costs and constant per-episode drug costs has led to increased total outpatient costs. But this has been offset by a dramatic dro[...]
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