Infectious diseases

  • Vaccine delivery costs challenge physicians

    on June 15th, 2017
    FROM ACADEMIC PEDIATRICS Payments from all types of payers did not cover pediatric vaccine delivery costs, many survey respondents from private, single-specialty practices said in 2011, reported Mandy A. Allison, MD, of the University of Colorado at Denver, Aurora, and her associates. Using the Amer[...]
  • Prophylaxis prevents PCP in rheumatic disease patients

    on June 15th, 2017
    AT THE EULAR 2017 CONGRESS MADRID (FRONTLINE MEDICAL NEWS) – The benefits of primary prophylaxis for pneumocystis pneumonia (PCP) outweighed the risks of treatment in patients taking prolonged, high-dose corticosteroids for various rheumatic diseases in a study presented at the European Congress o[...]
  • All isn’t well with HIV-exposed uninfected infants

    on June 15th, 2017
    AT ESPID 2017 MADRID (FRONTLINE MEDICAL NEWS) – Children who were HIV-exposed antenatally but not infected are at double the risk of hospitalization for infectious diseases during their first year of life, compared with HIV-unexposed controls, according to what’s believed to be the first prospec[...]
  • Hexavalent DTaP5-IPV-HB-Hib is immunogenic in series with pentavalent vaccine

    on June 15th, 2017
    FROM VACCINE DTaP5-inactivated polio vaccine (IPV)-hepatitis B (HB)-Haemophilus influenzae type b (Hib) used in a series with DTaP5-IPV-Hib showed strong immune responses against all the hexavalent antigens, said Federico Martinón-Torres, MD, of Hospital Clinico Universitario de Santiago de Compost[...]
  • E. coli, GBS account for majority of neonatal bacterial meningitis in Canada

    on June 15th, 2017
    FROM PEDIATRICS No major shifts appear to have occurred in the bacteria that cause meningitis in Canada, said Lynda Ouchenir, MD, University of Montreal, and her associates. “There is a paucity of information on the characteristics of neonatal meningitis in the era of infant Haemophilus influenzae[...]
  • Whole blood PCR improves diagnosis of pediatric bacterial sepsis

    on June 14th, 2017
    AT ESPID 2017 MADRID (FRONTLINE MEDICAL NEWS) – Whole blood multiplex polymerase chain reaction (PCR) holds considerable promise as a rapid noninvasive test to improve diagnosis of life-threatening bacterial infections in children with suspected sepsis yet negative blood cultures, Clare Thakker, M[...]
  • Earlier childhood measles vaccination elevates the risk of vaccine failure

    on June 14th, 2017
    FROM CLINICAL INFECTIOUS DISEASES Antibody responses in children born to vaccinated mothers were lower because of earlier administration of their first measles vaccine dose at 12 months of age or younger, compared with 15 months of age or older, said Sara Carazo Perez, MD, PhD, of Laval University, [...]
  • Investigational flu vaccine finds way around pyrogenicity problem

    on June 14th, 2017
    FROM VACCINE An investigational quadrivalent flu vaccine formulated to be less pyrogenic had noninferior immunogenicity, compared with a U.S.-licensed vaccine, in children aged 5-17 years, Jolanta Airey, MD, of Seqirus in Parkville, Australia, and her associates reported. In 2010, in Australia and N[...]
  • Steatosis linked to persistent ALT increase in hepatitis B

    on June 12th, 2017
    FROM CLINICAL GASTROENTEROLOGY AND HEPATOLOGY About one in five patients with chronic hepatitis B virus (HBV) infection had persistently elevated alanine aminotransferase (ALT) levels despite long-term treatment with tenofovir disoproxil fumarate, according to data from two phase III trials reported[...]
  • When fecal transplants for C. diff. fail, try, try again

    on June 12th, 2017
    AT DDW 2017 CHICAGO (FRONTLINE MEDICAL NEWS) – The best remedy for a failed fecal microbiota transplant for recurrent Clostridium difficile infection is most likely a second – or even a third or fourth attempt, according to Monika Fischer, MD. Fecal microbiota transplants (FMTs) cure the large m[...]
  • Rapid culture, stewardship improve S. aureus bacteremia outcomes

    on June 12th, 2017
    AT ASM MICROBE 2017 NEW ORLEANS (FRONTLINE MEDICAL NEWS) – Community hospitals could see positive outcomes using a Staphylococcus aureus bacteremia strategy that combines rapid blood cultures to speed diagnosis with antibiotic stewardship to guide treatment. Many academic medical centers report im[...]
  • CDC: First-trimester Zika infection had highest rate of birth defects

    on June 8th, 2017
    FROM MMWR One in 12 infant or fetus born to mothers from the U.S. territories with laboratory-confirmed Zika infection during the first trimester had a birth defect possibly-associated with the infection, officials from the Centers for Disease Control and Prevention reported. Overall, there were 3,9[...]
  • Factors tied to parents’ intent to vaccinate teens for HPV

    on June 8th, 2017
    FROM PREVENTING CHRONIC DISEASE Mothers with a lower level of education had a stronger intent to vaccinate their teen for human papillomavirus (HPV) than college-educated mothers in a large study, said Kahee A. Mohammed, MD, of Saint Louis (Missouri) University Center for Outcomes Research, and asso[...]
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