Infectious diseases

  • HCV ‘cure’ within the VA appears likely

    on March 16th, 2017
    FROM ALIMENTARY PHARMACOLOGY AND THERAPEUTICS The number of Veterans Affairs patients with hepatitis C who have achieved a sustained virologic response to antiviral therapy has escalated so rapidly and reached such a height that the disease may well be eradicated in that health care system within a [...]
  • Infant hepatitis B vaccine protection lingers into adolescence

    on March 15th, 2017
    FROM THE PEDIATRIC INFECTIOUS DISEASE JOURNAL Adolescents who received hepatitis B virus (HBV) vaccinations as infants still showed protection despite little evidence of residual antibodies, a study showed. This finding was based on data from a prospective study of 137 children, aged 10-11 years, an[...]
  • How to ‘de-label’ penicillin allergies in the hospital

    on March 15th, 2017
    AT THE 2017 AAAAI ANNUAL MEETING ATLANTA (FRONTLINE MEDICAL NEWS) – With the help of a pharmacist and the electronic health records system, Rochester (N.Y.) General Hospital ruled out penicillin allergies in 47 of 50 adult inpatients, and successfully transitioned them from second-line antibiotics[...]
  • Pneumococcal conjugate vaccine beats Streptococcus pneumoniae bacteremia

    on March 14th, 2017
    FROM PEDIATRICS Routine use of the 13-valent pneumococcal conjugate vaccine (PCV13) reduced the incidence of Streptococcus pneumoniae bacteremia by 95% from a time period before to a time period after the vaccine was implemented, based on a review of more than 57,000 blood cultures from children age[...]
  • FDA committee approves strains for 2017-2018 flu shot

    on March 13th, 2017
    At AN FDA ADVISORY COMMITTEE MEETING ROCKVILLE, MD. (FRONTLINE MEDICAL NEWS) – A committee of Food and Drug Administration advisers backed the World Health Organization’s influenza vaccine recommendations for the 2017-2018 season at a meeting March 9. In a unanimous vote, members of the Vaccines[...]
  • U.S. chikungunya epidemic would likely put rheumatologists on front line

    on March 13th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – The continental United States is vulnerable to an epidemic of chikungunya virus disease, an event which would have profound consequences for rheumatologists, Robert T. Schoen, MD, said at the Winter R[...]
  • HCV testing stagnant among baby boomers

    on March 10th, 2017
    FROM AMERICAN JOURNAL OF PREVENTIVE MEDICINE Despite the urging of the United States Preventive Services Task Force and other organizations in 2013, the percentage of baby boomers who underwent testing for hepatitis C (HCV) infection had barely changed 2 years later – from 12.3% in 2013 to 13.8% i[...]
  • Five-day treatment of ear infections

    on March 10th, 2017
    In December 2016, the results of a randomized, controlled trial of 5-day vs. 10-day amoxicillin/clavulanate treatment of acute otitis media (AOM) in children aged 6-23 months was reported by Hoberman et al. in the New England Journal of Medicine (NEJM).1 Predefined criteria for clinical failure were[...]
  • Norovirus reporting tool yields real-time outbreak data

    on March 9th, 2017
    from the morbidity and mortality weekly report NoroSTAT, the Centers for Disease Control and Prevention’s new program with which states can report norovirus outbreaks, yields more timely and more complete epidemiologic and laboratory data, which allows a faster and better-informed public health re[...]
  • Cervicovaginal microbiota correlates with preterm birth rate

    on March 7th, 2017
    AT THE PREGNANCY MEETING LAS VEGAS (FRONTLINE MEDICAL NEWS) – Certain cervicovaginal microbiota predispose women to spontaneous preterm birth, according to a new study, while other microbiota were found to be protective against preterm delivery. The findings stand in contrast to previous clinical [...]
  • DTaP5-IPV noninferior to DTaP5 plus IPV for fifth dose

    on March 3rd, 2017
    FROM THE PEDIATRIC INFECTIOUS DISEASE JOURNAL The stand-alone diphtheria, tetanus, acellular, pertussis and inactivated poliovirus combination vaccine – DTaP5-IPV – is equivalent as a fifth dose to the separate DTaP5 plus IPV vaccines in children aged 4-6 years, according to a noninferiority stu[...]
  • Zika-infected pregnancies continue to rise in U.S.

    on March 3rd, 2017
    Reports of new cases of Zika infection in pregnant women held steady during the 2 weeks ending Feb. 21 as the number of new cases dropped in the territories and rose in the 50 states and D.C., according to the Centers for Disease Control and Prevention. Compared with the previous 2-week period (Jan.[...]
  • Chikungunya implicated in long-term joint disease

    on March 3rd, 2017
    FROM JOINT BONE SPINE A majority of Chikungunya infections can cause arthritis and arthralgia months or years after the initial infection, based on data from a prospective study of 307 patients. “The most common symptoms of Chikungunya virus infection are fever associated with rheumatic manifestat[...]
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