Infectious diseases

  • CDC reports two new Zika-related pregnancy losses

    on March 24th, 2017
    The first pregnancy losses with Zika-related birth defects since last summer were reported March 14 by the Centers for Disease Control and Prevention. Two new cases were reported to the U.S. Zika Pregnancy Registry between Feb. 21 and March 14 – the time period covered by the most recent release o[...]
  • Novel antifungal had favorable safety, efficacy profile for onychomycosis in phase IIB study

    on March 23rd, 2017
    AT AAD 17 ORLANDO (FRONTLINE MEDICAL NEWS) – A novel orally administered antifungal showed a favorable safety and efficacy profile in the treatment of distal lateral subungual onychomycosis, in a phase IIB study presented at the annual meeting of the American Academy of Dermatology. In the RENOVAT[...]
  • New self-persuasion app to promote HPV vaccine appears effective

    on March 22nd, 2017
    FROM PATIENT EDUCATION & COUNSELING A new tablet application using a self-persuasion method has been successful in convincing parents in underserved communities to have their children vaccinated for human papillomavirus (HPV), according to a study. Of 45 participating parents, 27 of the 33 (82%)[...]
  • Hepatitis Outlook: Late February 2017

    on March 22nd, 2017
    If you work on the front lines of medical care, treating patients with hepatitis, you may not have time to review all the hepatitis research that enters the medical literature every month. Here’s a quick look at some notable news items and journal articles published over the past month, which cove[...]
  • Dexmedetomidine improves sedation in sepsis

    on March 21st, 2017
    FROM ISICEM Use of dexmedetomidine improved sedation among ventilated patients with sepsis, but did not significantly cut mortality rates or increase ventilator-free days in a multicenter, open-label randomized controlled trial. Twenty-eight days after the start of mechanical ventilation, cumulative[...]
  • Norepinephrine shortage linked to mortality in patients with septic shock

    on March 21st, 2017
    FROM ISICEM A national shortage of norepinephrine in the United States was associated with higher rates of mortality among patients hospitalized with septic shock, investigators reported. Rates of in-hospital mortality in 2011 were 40% during quarters when hospitals were facing shortages and 36% whe[...]
  • HIV vaccine could prevent 30 million cases by 2035

    on March 20th, 2017
    FROM PNAS Global cases of HIV from 2015 to 2035 would be reduced by over 50% if the Joint United Nations Program on HIV/AIDS 95/95/95 target is met and a moderately effective HIV vaccine is introduced by 2020, according to new research published in Proceedings of the National Academy of Sciences. A [...]
  • U.S. influenza activity remains steady

    on March 20th, 2017
    The decline in U.S. influenza activity that started in February paused during the week ending March 11, according to the U.S. Centers for Disease Control and Prevention. The proportion of outpatient visits for influenza-like illness (ILI) stayed at 3.7% for a second consecutive week after declining [...]
  • Influenza vaccine is underused in children with heart disease

    on March 20th, 2017
    FROM THE JOURNAL OF PEDIATRICS The influenza vaccine is underused in children with heart disease; approximately one-third were vaccinated in a prospective study of 186 children in September and October 2012. “Annual influenza vaccination is the most effective and safe means of preventing the disea[...]
  • HIV research update: Late February 2017

    on March 17th, 2017
    A great volume of HIV and AIDS research enters the medical literature every month. It can be difficult to monitor everything, so here’s a quick look at some notable news items and journal articles published over the past few weeks. Targeted recruitment of hospitalized populations is a feasible and[...]
  • Zika virus linked to heart failure, arrhythmias

    on March 17th, 2017
    FROM ACC 17 WASHINGTON (FRONTLINE MEDICAL NEWS) – Patients infected with the Zika virus may have an increased risk of heart failure, arrhythmias, and myocarditis, according to a small study. Observations were conducted of nine patients – six of whom were female with a mean age of 47 years – wh[...]
  • Antiviral medication successful for treating HCV in hepatocellular carcinoma

    on March 16th, 2017
    FROM JOURNAL OF HEPATOLOGY Direct-acting antiviral (DAA) medication was successful in treating hepatitis C in 74.5% of patients with hepatocellular carcinoma, and 93.4% of patients with HCC who underwent liver transplants, according to a study funded by Veterans Affairs. In order to study the effect[...]
  • HCV ‘cure’ within the VA appears likely

    on March 16th, 2017
    FROM ALIMENTARY PHARMACOLOGY AND THERAPEUTICS The number of Veterans Affairs patients with hepatitis C who have achieved a sustained virologic response to antiviral therapy has escalated so rapidly and reached such a height that the disease may well be eradicated in that health care system within a [...]
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