Infectious diseases

  • Study shows that 20% of inpatients given antibiotics develop adverse reactions

    on June 26th, 2017
    FROM JAMA INTERNAL MEDICINE Twenty percent of hospitalized adults given antibiotics develop adverse drug events, including GI, nephrotoxic, hematologic, cardiac, and neurotoxic effects, according to a report in JAMA Internal Medicine. This high frequency of adverse reactions “may not be recognized[...]
  • Safety data review finds no increased risk of infection from abatacept

    on June 24th, 2017
    AT EULAR 2017 MADRID (FRONTLINE MEDICAL NEWS) – Abatacept doesn’t appear to increase the risk of opportunistic infections among patients with rheumatoid arthritis, Kevin Winthrop, MD, reported at the European Congress of Rheumatology. After reviewing all of the extant safety data on the drug –[...]
  • ACIP approves new influenza vaccine recommendations

    on June 23rd, 2017
    FROM AN ACIP MEETING New draft recommendations on influenza vaccines for children and pregnant women were unanimously passed by the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) after a lengthy debate over specifics regarding recommendations for p[...]
  • If doctors recommend it, teens are more likely to get HPV vaccine

    on June 23rd, 2017
    FROM PAPILLOMAVIRUS RESEARCH Physician recommendation was the most common reason parents began human papillomavirus (HPV) vaccination for their adolescents, Brandon Brown, PhD, at the University of California, Riverside, and his associates said. In a year-long survey of 200 parents’ reasons for ag[...]
  • ACIP approves new hepatitis A vaccine draft recommendations

    on June 22nd, 2017
    FROM ACIP MEETING The Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices (ACIP) approved new recommendations for hepatitis A vaccinations, including a focus on catch up vaccines for adolescents and those over age 40 years. While hepatitis A cases have dropped[...]
  • Dengue vaccine appears safe, immunogenic in children aged 2-17 years

    on June 21st, 2017
    FROM LANCET INFECTIOUS DISEASES An investigational dengue vaccine against all four serotypes appears to be safe and immunogenic in children aged 2-17 years, whether or not they previously have been exposed to the virus, said Xavier Sáez-Llorens, MD, of Hospital del Niño Dr José Renán Esquivel, P[...]
  • Tipoffs that an infant hospitalized with pertussis may require ICU

    on June 21st, 2017
    AT ESPID 2017 MADRID (FRONTLINE MEDICAL NEWS) – Infants hospitalized for pertussis are more likely to develop severe disease requiring pediatric ICU admission if they are experiencing apnea, are unvaccinated against pertussis, or are less than 2 months old, Maria Arranz, MD, reported at the annual[...]
  • Consider college immunization requirements when counseling about vaccines

    on June 20th, 2017
    FROM VACCINE Clinicians who are counseling vaccine-hesitant parents about vaccination may want to consider adding immunization requirements of universities to their armamentarium, recommended Allison Noesekabel, a medical student at Wayne State University, Detroit, and Ada M. Fenick, MD , a pediatri[...]
  • HCV/HIV-coinfected teens rapidly progress to advanced liver disease

    on June 20th, 2017
    AT ESPID 2017 MADRID (FRONTLINE MEDICAL NEWS) – Roughly one in four children with vertically transmitted hepatitis C virus (HCV)/HIV coinfection will progress to advanced hepatic fibrosis by age 20 years despite treatment with pegylated interferon plus ribavirin, Carolina Fernández McPhee, MD, re[...]
  • MMR vaccine cut hospitalizations for unrelated respiratory infections

    on June 20th, 2017
    FROM HUMAN VACCINES & IMMUNOTHERAPEUTICS The MMR vaccine appears to reduce pediatric hospitalizations not only for measles and mumps, but also for unrelated respiratory infections, said Giuseppe La Torre of the Sapienza University of Rome and his associates. The 2-year retrospective database stu[...]
  • FDA approves new fluoroquinolone for skin, skin structure infections

    on June 19th, 2017
    The Food and Drug Administration has approved delafloxacin, a fluoroquinolone, for the treatment of acute bacterial skin and skin structure infections, according to an agency announcement June 19. Delafloxacin, which will be marketed by Melinta Therapeutics as Baxdela, was designated a qualified inf[...]
  • Monoclonal antibody holds promise for S. aureus pneumonia

    on June 16th, 2017
    AT ASM MICROBE 2017 NEW ORLEANS (FRONTLINE MEDICAL NEWS) – Monoclonal antibody therapies have already upended treatment strategies in cancer, dermatology, and multiple inflammatory diseases, and infectious disease may be next. That’s because a single injection of a monoclonal antibody in develop[...]
  • Measles immunization is a major challenge in HIV-infected children

    on June 16th, 2017
    AT ESPID 2017 MADRID (FRONTLINE MEDICAL NEWS) – Impaired response to measles immunization is common in HIV-infected children, and revaccination – while an important strategy – helps only some of them, Ruth del Valle, MD, said at the annual meeting of the European Society for Paediatric Infecti[...]
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