• Infectious enteritis quadrupled short-term risk of IBS

    on February 24th, 2017
    FROM GASTROENTEROLOGY More than 10% of patients developed irritable bowel syndrome (IBS) within a year after infectious enteritis, which gave them a more than fourfold greater risk than that of controls, according to a systematic review and meta-analysis of 45 studies. “Protozoal and bacterial ent[...]
  • Unrestricted DAA access halved Dutch HCV incidence in HIV

    on February 23rd, 2017
    AT CROI SEATTLE (FRONTLINE MEDICAL NEWS) – New hepatitis C infections among HIV-positive men who have sex with men (MSM) were halved in the Netherlands by unrestricted access to direct-acting antivirals (DAAs), primarily ledipasvir/sofosbuvir tablets (Harvoni), according to Dutch investigators. Si[...]
  • Inactivated hepatitis A vaccine shows promise in 5-year study

    on February 23rd, 2017
    FROM HUMAN VACCINES & IMMUNOTHERAPEUTICS A single dose of an inactivated hepatitis A virus (HAV) vaccine resulted in high seropositive rates and antibody concentrations, persisting for at least 5 years in children, a study has shown. In October 2008, a team of investigators in China led by Zhilu[...]
  • Factors may flag kids at high risk for C. difficile recurrence

    on February 22nd, 2017
    FROM THE PEDIATRIC INFECTIOUS DISEASE JOURNAL The identification of risk factors associated with recurrent Clostridium difficile infection (rCDI) might allow early recognition of those children at highest risk, said Dr. Maribeth Nicholson of Vanderbilt University, Nashville, Tenn., and her associate[...]
  • FDA confirms complications from intragastric balloons

    on February 22nd, 2017
    Complications from overinflation and acute pancreatitis can create problems for obesity patients treated with intragastric balloons, according to a statement from the Food and Drug Administration. In a letter to health care providers published on February 9, 2017, the FDA warned of the two specific [...]
  • Gluten-free diets related to high levels of arsenic, mercury

    on February 22nd, 2017
    FROM EPIDEMIOLOGY Individuals who adopt a gluten-free diet are putting themselves at risk for uncommonly high levels of arsenic and mercury, according to the findings of a recent study published in Epidemiology. “Despite [less than] 1% of Americans having diagnosed celiac disease, an estimated 25%[...]
  • LEEP tops cryotherapy for cervical dysplasia in women with HIV

    on February 21st, 2017
    AT CROI SEATTLE (FRONTLINE MEDICAL NEWS) – HIV-positive women treated with cryotherapy for cervical intraepithelial neoplasia (CIN) 2/3 were 52% more likely than women treated with loop excision to have a recurrence within 2 years, according to a randomized trial in Kenya. The investigators called[...]
  • Urgent colonoscopy for LGIB: Consider case by case

    on February 17th, 2017
    FROM GASTROINTESTINAL ENDOSCOPY Colonoscopy performed within 24 hours of lower gastrointestinal bleeding appears safe and well tolerated but does not appear to improve a number of important clinical outcomes when compared with elective colonoscopy, according to the findings of a systematic review an[...]
  • Hepatitis Outlook: January 2017

    on February 15th, 2017
    If you work on the front lines of medical care treating patients with hepatitis, you may not have time to review all the hepatitis research that enters the medical literature every month. Here’s a quick look at some notable news items and journal articles published over the past month, covering th[...]
  • Fecal microbiota transplantation a decolonization treatment option

    on February 13th, 2017
    FROM THE JOURNAL OF HOSPITAL INFECTION The use of fecal microbiota transplantation is an option to eradicate highly drug-resistant enteric bacteria carriage, according to results from a small pilot study conducted by French investigators. “A rapid and dramatic emergence of highly drug-resistant en[...]
  • ACR guidelines on HBV screening called inadequate

    on February 13th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – The ACR guidelines for hepatitis B virus screening prior to starting immunosuppressive therapy are sorely in need of an overhaul, Leonard H. Calabrese, MD, asserted at the Winter Rheumatology Symposiu[...]
  • Eradicate HCV in patients with HIV, regardless of fibrosis stage

    on February 12th, 2017
    FROM HEPATOLOGY Eradicating hepatitis C virus in HIV-coinfected patients was associated with a significantly lower risk of diabetes mellitus and possibly chronic renal failure, along with lower rates of deaths, HIV progression, and liver-related events, according to an observational study of 1,625 p[...]
  • Rituximab is dramatically effective in IgG4-related disease

    on February 10th, 2017
    EXPERT ANALYSIS FROM THE WINTER RHEUMATOLOGY SYMPOSIUM SNOWMASS, COLO. (FRONTLINE MEDICAL NEWS) – Glucocorticoids remain the first-line therapy in immunoglobulin G4-related disease, but it’s essential to bear in mind that their long-term efficacy in this immune-mediated fibroinflammatory disease[...]
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