• Norfloxacin improves short-term advanced cirrhosis survival

    on April 28th, 2017
    AT ILC 2017 AMSTERDAM (FRONTLINE MEDICAL NEWS) – Prolonged oral treatment with norfloxacin improved the survival of patients with Child-Pugh class C liver disease versus no antibiotic prophylaxis in a randomized, double-blind, placebo-controlled, phase III multicenter trial. Fewer patients (15.3% [...]
  • Distance from transplant center predicted mortality in chronic liver disease

    on April 27th, 2017
    Living more than 150 miles from a liver transplant center was associated with a higher risk of mortality among patients with chronic liver failure, regardless of etiology, transplantation status, or whether patients had decompensated cirrhosis or hepatocellular carcinoma, according to a first-in-kin[...]
  • Project Sonar brings gastroenterologists one step closer to a specialty-specific APM

    on April 27th, 2017
    Gastroenterologists wanting to participate in the advanced alternative payment model track of the new Quality Payment Program developed under the Medicare Access and CHIP Reauthorization Act (MACRA) may soon have an option as early as 2018. Project Sonar , a program that helps gastroenterologists an[...]
  • Start probiotics within 2 days of antibiotics to prevent CDI, study suggests

    on April 26th, 2017
    FROM GASTROENTEROLOGY Starting probiotics within 2 days of the first antibiotic dose could cut the risk of Clostridium difficile infection among hospitalized adults by more than 50%, according to the results of a systemic review and metaregression analysis. The protective effect waned when patients [...]
  • Medicine’s revenge against traveler’s diarrhea

    on April 26th, 2017
    Traveler’s diarrhea (TD) is the most common illness in people traveling from resource-advantaged countries to resource-limited regions of the globe. Approximately 50% of these types of travelers will contract diarrhea. I knew of a group of infectious disease experts traveling to India together –[...]
  • Long-term albumin shows survival benefit in decompensated cirrhosis

    on April 25th, 2017
    AT ILC 2017 AMSTERDAM (FRONTLINE MEDICAL NEWS) – Long-term treatment with human albumin improved the overall survival of patients with decompensated liver cirrhosis, compared with standard medical care, in a randomized, controlled trial presented at the International Liver Congress. The final resu[...]
  • Study confirms uneven access to liver cancer treatment at VA hospitals

    on April 24th, 2017
    FROM GASTROENTEROLOGY Only 25% of Veterans Affairs (VA) patients with potentially curable (Barcelona Clinic Liver Cancer stage 0/A) hepatocellular carcinoma received resection, transplantation, or ablative therapy, according to the results of a national retrospective cohort study published in the Ju[...]
  • WHO report sets baseline for viral hepatitis elimination

    on April 23rd, 2017
    AT ILC 2017 AMSTERDAM (FRONTLINE MEDICAL NEWS) – An estimated 328 million people worldwide were living with chronic hepatitis B or C virus infection in 2015 according to a new report issued by the World Health Organization and launched at the International Liver Congress sponsored by the European [...]
  • Renflexis approved as second infliximab biosimilar

    on April 21st, 2017
    Infliximab-abda is the second infliximab biosimilar approved by the Food and Drug Administration, the agency announced April 21. Infliximab-abda, to be marketed as Renflexis, is approved for all indications as the reference product, including Crohn’s diseases in adults and children, ulcerative col[...]
  • DTC genetic health risk tests: Beware

    on April 21st, 2017
    The Food and Drug Administration recently authorized 23andMe to provide consumers with results of germline DNA sequence variants associated with risk for 10 health conditions, among them hereditary hemochromatosis, alpha-1 antitrypsin deficiency, celiac disease, Alzheimer’s disease, and Parkinson[...]
  • CDC: Some Shigella strains show reduced ciprofloxacin susceptibility

    on April 21st, 2017
    The Centers for Disease Control and Prevention has identified an increase in Shigella isolates with reduced susceptibility to ciprofloxacin, and has released an official health advisory outlining new recommendations for clinical diagnosis, management, and reporting, as well as for laboratories and p[...]
  • Dactylitis, enthesitis, anterior uveitis less frequent in IBD-SpA

    on April 20th, 2017
    FROM THE JOURNAL OF RHEUMATOLOGY In patients with inflammatory bowel disease and spondyloarthritis (IBD-SpA), dactylitis, enthesitis, and anterior uveitis (AU) are significantly less frequent than in patients with other types of SpA, according to Fabrizio Cantini, MD, and his associates. In a 12-mon[...]
  • Three-strategy combo reduces pancreatoduodenectomy fistula risk

    on April 19th, 2017
    AT AHPBA 2017 MIAMI BEACH (FRONTLINE MEDICAL NEWS) – Pancreaticojejunostomy reconstruction, use of stents, and avoidance of prophylactic octreotide, especially in combination, could reduce the fistula rate associated with pancreatoduodenectomy. Failure of the anastomosis is “of greatest concern[...]
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