Emergency Trauma

  • CARs race for supremacy against aggressive non-Hodgkin lymphoma

    on June 25th, 2017
    AT EHA 2017 MADRID – Two chimeric antigen receptor T cell (CAR-T) constructs are showing promising activity against treatment-refractory, aggressive forms of non-Hodgkin lymphoma in multicenter clinical trials. In the ZUMA-1 trial, axicabtagene ciloleucel (axi-cel), an autologous anti-CD19 CAR-T p[...]
  • For opioid-related hospitalizations, men and women are equal

    on June 22nd, 2017
    Equality is not always a good thing, particularly with opioids. In 2005, the rate of opioid-related inpatient hospital stays was 145.6 per 100,000 population for males of all ages and 127.8 for females of all ages. By 2014, however, equality had arrived: Females had a rate of 224.1 per 100,000, comp[...]
  • Angiotensin II may improve vasopressors’ efficacy

    on June 14th, 2017
    At ATS 2017 WASHINGTON (FRONTLINE MEDICAL NEWS) – Adding angiotensin II to available vasopressor therapies correlated with significantly improved arterial pressure in patients with catecholamine-resistant vasodilatory shock and less adverse effects, according to a study presented at the recent int[...]
  • Noninvasive therapy cut COPD readmissions

    on June 7th, 2017
    FROM ATS 2017 WASHINGTON (FRONTLINE MEDICAL NEWS) – The addition of noninvasive ventilation to home oxygen therapy regimens correlated with increased time to readmission or death among patients with exacerbated chronic obstructive pulmonary diseases (COPD), according to a study presented at an int[...]
  • CORRECTION: VIDEO: Hyperinflammatory ARDS responds to simvastatin

    on June 5th, 2017
    In an article titled “VIDEO: Hyperinflammatory ARDS responds to simvastatin”, published June 2, 2017, Dr. Carolyn S. Calfee’s statement on the study results was misquoted. Hypoinflammatory patients treated with simvastatin may have improved outcomes, compared with hyperinflammatory patients tr[...]
  • VIDEO: Hyperinflammatory ARDS responds to simvastatin

    on June 2nd, 2017
    AT ATS 2017 WASHINGTON (FRONTLINE MEDICAL NEWS) – Acute respiratory distress syndrome (ARDS) appears to exist in at least two major forms, and one of these, the hyperinflammatory form, seemed responsive to simvastatin in a post-hoc analysis of trial data. The other version of ARDs is a hypoinflamm[...]
  • Recurrent acute pancreatitis significantly impairs both mental and physical quality of life

    on May 22nd, 2017
    AT DDW CHICAGO (FRONTLINE MEDICAL NEWS) – Despite its intermittent and unpredictable nature, recurrent acute pancreatitis exacts a significant toll on patients’ physical and mental quality of life. It is well-known that patients with chronic pancreatitis suffer physically and emotionally. Howeve[...]
  • Intravenous tPA ups mortality in children with acute ischemic stroke

    on May 17th, 2017
    AT AAN 2017 BOSTON (FRONTLINE MEDICAL NEWS) – Intravenous thrombolysis with tissue plasminogen activator (tPA) is associated with adverse outcomes, including an increased risk of death, in children with acute ischemic stroke, based on a review of cases from the 2006-2010 Nationwide Inpatient Surve[...]
  • FDA: Fluoroquinolone use not linked to retina detachment, aortic problems

    on May 11th, 2017
    The Food and Drug Administration has found no evidence of a link between fluoroquinolone usage and retinal detachment or aortic aneurysm and dissection, according to a new Drug Safety Communication update on potential serious, disabling side effects of oral and injectable fluoroquinolone antibiotics[...]
  • 24/7 neurologist coverage improved community hospital stroke outcomes

    on May 6th, 2017
    AT AAN 2017 BOSTON (FRONTLINE MEDICAL NEWS) – Around-the-clock availability of a neurologist for acute stroke treatment significantly reduced door-to-needle times at a community-based primary stroke center serving as a regional tertiary referral center for western North Carolina. For each minute o[...]
  • Watchful waiting a suitable option for pediatric acute ITP

    on May 4th, 2017
    FROM ASPHO 2017 MONTREAL (FRONTLINE MEDICAL NEWS) – Clinicians who manage the care of children with newly diagnosed idiopathic thrombocytopenic purpura (ITP) have to decide whether to treat patients early and possibly increase risk for chronic ITP down the road or to leave well enough alone and tr[...]
  • Prenotification, unequivocal stroke promote ultra-fast door-to-needle time

    on April 24th, 2017
    AT AAN 2017 BOSTON (FRONTLINE MEDICAL NEWS) – Ultra-fast door-to-needle times of 10 minutes or less for intravenous acute ischemic stroke thrombolysis can be safely achieved in carefully selected cases, according to a review of cases at an Austrian teaching hospital. Raffi Topakian, MD , and his c[...]
  • Clearer heads are a fuzzy subject

    on April 20th, 2017
    Those of you who were in high school or middle school in 1987, when the DSM II-R first included “Attention Deficit Disorder With and Without Hyperactivity” for the first time, missed out on the “discovery,” and subsequent commercialization, of a condition that had been percolating under phys[...]
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